INT153733

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.47
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 3
Disease Relevance 0
Pain Relevance 2.39

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endoplasmic reticulum (Gria2) plasma membrane (Gria2) protein complex (Gria2)
Anatomy Link Frequency
amygdala 5
hippocampus 1
Gria2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
amygdala 12 99.68 Very High Very High Very High
Hippocampus 12 99.16 Very High Very High Very High
Morphine 18 98.94 Very High Very High Very High
antagonist 3 70.56 Quite High
agonist 3 44.72 Quite Low
opioid receptor 3 44.36 Quite Low

|}

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The decreases in GluR2 mRNA expression in the amygdala and hippocampus may result in the formation of calcium-permeable AMPA receptors, which are believed to play an important role in behavioural sensitization.
Negative_regulation (decreases) of Transcription (expression) of GluR2 in amygdala associated with hippocampus and amygdala
1) Confidence 0.47 Published 2008 Journal Clin. Exp. Pharmacol. Physiol. Section Abstract Doc Link 18671727 Disease Relevance 0 Pain Relevance 0.76
In addition, repeated morphine treatment followed by 7 days (but not 24 h) washout decreased GluR2 mRNA expression in both the amygdala (by 50%) and hippocampus (by 35%).
Negative_regulation (decreased) of Transcription (expression) of GluR2 in amygdala associated with hippocampus, amygdala and morphine
2) Confidence 0.35 Published 2008 Journal Clin. Exp. Pharmacol. Physiol. Section Abstract Doc Link 18671727 Disease Relevance 0 Pain Relevance 0.86
The decreases in GluR2 mRNA expression in the amygdala and hippocampus may result in the formation of calcium-permeable AMPA receptors, which are believed to play an important role in behavioural sensitization.
Negative_regulation (decreases) of in hippocampus Transcription (expression) of GluR2 in amygdala associated with hippocampus and amygdala
3) Confidence 0.16 Published 2008 Journal Clin. Exp. Pharmacol. Physiol. Section Abstract Doc Link 18671727 Disease Relevance 0 Pain Relevance 0.76

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox