INT15386

Context Info Confidence 0.49 First Reported 1991 Last Reported 2008 Negated 0 Speculated 0 Reported most in Body Documents 2 Total Number 2 Disease Relevance 0.91 Pain Relevance 0.08

plasma membrane (CD79A)

CD79A (Homo sapiens)

Pain Link Frequency Relevance Heat headache 1 83.36 rheumatoid arthritis 30 50.00 Inflammation 21 5.00 cINOD 1 5.00 Rheumatism 1 5.00 Infliximab 1 5.00

Disease Link Frequency Relevance Heat Obesity 16 96.12 Acute-phase Reaction 2 93.60 Disorder Of Lipid Metabolism 17 87.96 Fatigue 1 86.04 Headache 1 83.36 Brain Injury 1 80.12 Syndrome 1 79.16 Disease 18 75.32 Rheumatoid Arthritis 30 50.00 INFLAMMATION 22 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

A lower level of IgA, IgG and lysozyme was only noted in individuals with occupational exposure exceeding 20 years.

Positive_regulation (noted) of Negative_regulation (level) of IgA

1) Confidence 0.49 Published 1991 Journal J Hyg Epidemiol Microbiol Immunol Section Abstract Doc Link 1725175 Disease Relevance 0.50 Pain Relevance 0.08

When effects of the different diet regimens were compared between groups at 12 months, BMI (F = 6.6, p = 0.0024), weight (F = 8.9, p = 0.003), and LDL (F = 18.8, p < 0.0001) were significantly lower and anti-PC IgM (F = 8.0, p = 0.0006) was higher in the vegan diet group whereas the increase in anti-PC IgA and decrease in oxLDL differed only trendwise (F = 2.5, p = 0.084 and F = 2.6, p = 0.081, respectively).

Positive_regulation (increase) of Negative_regulation (decrease) of IgA associated with obesity

2) Confidence 0.05 Published 2008 Journal Arthritis Res Ther Section Body Doc Link PMC2453753 Disease Relevance 0.41 Pain Relevance 0

General Comments

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