INT153860

Context Info Confidence 0.14 First Reported 2008 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 2 Total Number 6 Disease Relevance 0.27 Pain Relevance 0.70

molecular_function (Ept1) cellular_component (Ept1) biological_process (Ept1)

Anatomy Link Frequency spinal cord 1 Ept1 (Mus musculus)

Pain Link Frequency Relevance Heat Spinal cord 7 99.12 Dermatone 3 91.84 Acupuncture 105 78.80 Pain 126 72.72 spinothalamic 1 69.76 Dorsal column 1 67.56 Dorsal horn 1 66.44 transcutaneous nerve stimulation 25 15.28 Pain threshold 35 5.00 Paresthesia 5 5.00

Disease Link Frequency Relevance Heat Frailty 4 75.00 Pain 161 72.72 Nociception 5 5.00 Dysesthesia 5 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

The relationship between EPT and dSSEP interpretation, dSSEP early onset latency and perceptual stimulation intensity, and the dissociation of EPT from EPP suggests that EPT is conducted within the posterior spinal cord.

Positive_regulation (conducted) of EPT in spinal cord associated with spinal cord

1) Confidence 0.14 Published 2008 Journal J. Neurotrauma Section Abstract Doc Link 18687037 Disease Relevance 0.07 Pain Relevance 0.44

Among the 22 men, 13 of them (59%) reported an increase of the EPT and the remaining 9 (41%) a decrease (Figure 6b).

Positive_regulation (increase) of EPT

2) Confidence 0.12 Published 2010 Journal Chin Med Section Body Doc Link PMC2942886 Disease Relevance 0 Pain Relevance 0

Twenty-one (21) of the 23 women (91%) reported the EPT as increased while two of them (9%) reported it as unchanged after EA.

Positive_regulation (increased) of EPT

3) Confidence 0.12 Published 2010 Journal Chin Med Section Body Doc Link PMC2942886 Disease Relevance 0.06 Pain Relevance 0.06

The group related effect among the women was supported by the fact that 21 of the 23 responded with increased EPT after EA.

Positive_regulation (increased) of EPT

4) Confidence 0.08 Published 2010 Journal Chin Med Section Body Doc Link PMC2942886 Disease Relevance 0.07 Pain Relevance 0.11

On the other hand, the EPT results showed the opposite pattern of change where the women responded with a systematic change towards increased EPT after EA while the men remained unchanged.

Positive_regulation (increased) of EPT

5) Confidence 0.08 Published 2010 Journal Chin Med Section Body Doc Link PMC2942886 Disease Relevance 0.06 Pain Relevance 0.09

The difference of proportional changes between women and men in EPT was 33% (95% CI, 10% to 56%), i.e. the increase in assessed EPT was greater among the women than then in the men after EA.

Positive_regulation (increase) of EPT

6) Confidence 0.08 Published 2010 Journal Chin Med Section Body Doc Link PMC2942886 Disease Relevance 0 Pain Relevance 0

General Comments

This test has worked.