INT153994

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Context Info
Confidence 0.02
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.46
Pain Relevance 0.44

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Prkaca, TRPV1) transport (TRPV1) mitochondrion (Prkaca)
Golgi apparatus (Prkaca) protein complex (Prkaca) lipid metabolic process (TRPV1)
Prkaca (Mus musculus)
TRPV1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammatory mediators 2 96.60 Very High Very High Very High
Hyperalgesia 2 95.40 Very High Very High Very High
Pain 1 93.28 High High
Inflammation 1 89.44 High High
bradykinin 1 79.68 Quite High
Disease Link Frequency Relevance Heat
INFLAMMATION 3 96.20 Very High Very High Very High
Hyperalgesia 2 95.40 Very High Very High Very High
Injury 1 88.80 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Here, we show that modulation of the sensitivity of the heat-activated ion channel TRPV1 by the protein kinases PKA and PKC and by the phosphatase calcineurin depends on the formation of a signaling complex between these enzymes, the scaffolding protein AKAP79/150 and TRPV1.
Regulation (depends) of PKA Regulation (modulation) of TRPV1
1) Confidence 0.02 Published 2008 Journal Neuron Section Abstract Doc Link 18701070 Disease Relevance 0.46 Pain Relevance 0.44

General Comments

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