INT154057

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Context Info
Confidence 0.41
First Reported 2005
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 14
Total Number 14
Disease Relevance 9.72
Pain Relevance 1.12

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

molecular_function (Ear1) cellular_component (Ear1) biological_process (Ear1)
nuclease activity (Ear1)
Anatomy Link Frequency
eosinophil 7
sputum 1
nasal 1
Ear1 (Mus musculus)
Pain Link Frequency Relevance Heat
abdominal pain 19 92.28 High High
fibrosis 9 91.00 High High
headache 6 82.64 Quite High
alcohol 1 79.92 Quite High
Inflammation 160 75.04 Quite High
peripheral neuropathy 1 71.56 Quite High
Versed 2 62.88 Quite High
methotrexate 10 35.56 Quite Low
anesthesia 4 25.44 Quite Low
Bioavailability 4 12.16 Low Low
Disease Link Frequency Relevance Heat
Hypersensitivity 44 99.84 Very High Very High Very High
Bullous Skin Disease 75 99.24 Very High Very High Very High
Pulmonary Disease 217 99.10 Very High Very High Very High
Echinococcosis 80 98.96 Very High Very High Very High
Asthma 98 98.52 Very High Very High Very High
Loss Of Sense Of Smell 2 98.38 Very High Very High Very High
Fever 9 95.64 Very High Very High Very High
Dyspnea 17 95.00 High High
Abdominal Pain 19 92.28 High High
Fibrosis 8 91.00 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Furthermore, a correlation was detected between ECP levels and eosinophil rate, IgE and CRP levels of patients with CE (p = 0.01), while there was no correlation between ECP and ESR levels.
Gene_expression (levels) of ECP in eosinophil associated with echinococcosis
1) Confidence 0.41 Published 2009 Journal Mikrobiyol Bul Section Abstract Doc Link 19621614 Disease Relevance 0.60 Pain Relevance 0.08
No statistically significant difference in terms of symptoms was detected between patients with high ECP levels and normal ECP levels.
Gene_expression (levels) of ECP
2) Confidence 0.36 Published 2009 Journal Mikrobiyol Bul Section Abstract Doc Link 19621614 Disease Relevance 0.62 Pain Relevance 0.09
While age, gender, ESR, IgE and CRP levels of patients with high ECP levels were not significantly different from levels of patients with normal ECP levels, significantly different eosinophil counts were detected among patients with high ECP values when compared to patients with normal ECP values.
Gene_expression (values) of ECP in eosinophil
3) Confidence 0.36 Published 2009 Journal Mikrobiyol Bul Section Abstract Doc Link 19621614 Disease Relevance 0.58 Pain Relevance 0.06
While age, gender, ESR, IgE and CRP levels of patients with high ECP levels were not significantly different from levels of patients with normal ECP levels, significantly different eosinophil counts were detected among patients with high ECP values when compared to patients with normal ECP values.
Gene_expression (values) of ECP in eosinophil
4) Confidence 0.36 Published 2009 Journal Mikrobiyol Bul Section Abstract Doc Link 19621614 Disease Relevance 0.54 Pain Relevance 0.07
While age, gender, ESR, IgE and CRP levels of patients with high ECP levels were not significantly different from levels of patients with normal ECP levels, significantly different eosinophil counts were detected among patients with high ECP values when compared to patients with normal ECP values.
Gene_expression (levels) of ECP in eosinophil
5) Confidence 0.36 Published 2009 Journal Mikrobiyol Bul Section Abstract Doc Link 19621614 Disease Relevance 0.60 Pain Relevance 0.06
ECP was detected to be high in 35 (60%), IgE in 37 (63%), CRP in 29 (50%) and eosinophile count in 9 (15.5%) patients.
Gene_expression (detected) of ECP
6) Confidence 0.36 Published 2009 Journal Mikrobiyol Bul Section Abstract Doc Link 19621614 Disease Relevance 0.63 Pain Relevance 0.03
While age, gender, ESR, IgE and CRP levels of patients with high ECP levels were not significantly different from levels of patients with normal ECP levels, significantly different eosinophil counts were detected among patients with high ECP values when compared to patients with normal ECP values.
Gene_expression (levels) of ECP in eosinophil
7) Confidence 0.36 Published 2009 Journal Mikrobiyol Bul Section Abstract Doc Link 19621614 Disease Relevance 0.55 Pain Relevance 0.05
No statistically significant difference in terms of symptoms was detected between patients with high ECP levels and normal ECP levels.
Gene_expression (levels) of ECP
8) Confidence 0.36 Published 2009 Journal Mikrobiyol Bul Section Abstract Doc Link 19621614 Disease Relevance 0.62 Pain Relevance 0.09
Although all three parameters, Cdyn, GL and EF50, adequately reflected the pronounced EAR in allergic mice there was enhanced variation between GL vs.
Gene_expression (reflected) of EAR associated with hypersensitivity
9) Confidence 0.13 Published 2005 Journal Respir Res Section Body Doc Link PMC1316879 Disease Relevance 0.45 Pain Relevance 0
During octenol exposure subjective ratings of smell and nasal irritation were increased together with higher nasal lavage biomarker levels of eosinophil cationic protein, myeloperoxidase and lysozyme.
Gene_expression (levels) of eosinophil cationic protein in nasal associated with loss of sense of smell
10) Confidence 0.06 Published 2008 Journal Toxicol. Lett. Section Abstract Doc Link 18706986 Disease Relevance 0.42 Pain Relevance 0.18
ECP is reserved for patients with PV who fail drug therapy.
Gene_expression (reserved) of ECP associated with bullous skin disease
11) Confidence 0.04 Published 2007 Journal Therapeutics and Clinical Risk Management Section Body Doc Link PMC1936286 Disease Relevance 0.79 Pain Relevance 0.11
However, such treatment did reduce levels of albumin and eosinophil cationic protein in sputum samples obtained from patients with COPD (Grootendorst, Gauw, Benschop et al 2003).


Gene_expression (levels) of eosinophil cationic protein in sputum associated with pulmonary disease
12) Confidence 0.02 Published 2007 Journal International Journal of Chronic Obstructive Pulmonary Disease Section Body Doc Link PMC2699952 Disease Relevance 1.21 Pain Relevance 0.09
In patients with COPD, small but significant reductions in sputum levels of albumin and eosinophil cationic protein were observed.
Gene_expression (levels) of eosinophil cationic protein in eosinophil associated with pulmonary disease
13) Confidence 0.02 Published 2007 Journal International Journal of Chronic Obstructive Pulmonary Disease Section Body Doc Link PMC2699952 Disease Relevance 1.17 Pain Relevance 0.07
Recent work indicates that fecal levels of eosinophil cationic protein and eosinophil protein X may prove to be useful markers for intestinal morbidity.
Gene_expression (levels) of eosinophil cationic protein in eosinophil
14) Confidence 0.01 Published 2010 Journal The American Journal of Tropical Medicine and Hygiene Section Body Doc Link PMC2963968 Disease Relevance 0.95 Pain Relevance 0.13

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