INT154095
From wiki-pain
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Sentences Mentioned In
Key: | Protein | Mutation | Event | Anatomy | Negation | Speculation | Pain term | Disease term |
Axonal injury was a severe and acute event, insofar as serum pNF-H levels were not significantly elevated at early (EAE day 12) or late (EAE days 35 and 50) disease time points. | |||||||||||||||
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(2535)-injected mice receiving vehicle compared to control mice, and administration of Kihi-to resulted in significant increases in P-NF-H expression levels in CA1 radiatum, dentate gyrus, parietal cortex, perirhinal cortex and the striatum (Figures 3 and 7). | |||||||||||||||
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During axon regeneration, the developmental pattern of IFs resumes: Vimentin is re-upregulated and expression of mature IFs such as NF-L and NF-H decreases [11][15], [17], [27], [32]. | |||||||||||||||
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(2535)-injected mice receiving vehicle compared to control mice, and administration of Kihi-to resulted in significant increases in P-NF-H expression levels in CA1 radiatum, dentate gyrus, parietal cortex, perirhinal cortex and the striatum (Figures 3 and 7). | |||||||||||||||
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(2535)-injected mice receiving vehicle compared to control mice, and administration of Kihi-to resulted in significant increases in P-NF-H expression levels in CA1 radiatum, dentate gyrus, parietal cortex, perirhinal cortex and the striatum (Figures 3 and 7). | |||||||||||||||
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In MS, cerebrospinal fluid pNF-H levels increased in those with primary or secondary progressive disease, but in those with relapsing remitting disease pNF-H titers were elevated acutely and decreased later [40]. | |||||||||||||||
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Moreover, increased blood levels of pNF-H in some LHON patients suggest not all axons are lost but a number are still undergoing degeneration even many years after visual loss. | |||||||||||||||
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