INT154144

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Context Info
Confidence 0.43
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 9
Total Number 9
Disease Relevance 2.36
Pain Relevance 0.36

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

molecular_function (Tymp) cellular_component (Tymp) biological_process (Tymp)
Anatomy Link Frequency
tubes 1
smooth muscle 1
cavity 1
Tymp (Rattus norvegicus)
Pain Link Frequency Relevance Heat
cva 18 82.48 Quite High
Inflammation 18 81.20 Quite High
ischemia 95 75.56 Quite High
anesthesia 18 17.60 Low Low
cytokine 6 5.00 Very Low Very Low Very Low
Inflammatory mediators 6 5.00 Very Low Very Low Very Low
ketamine 5 5.00 Very Low Very Low Very Low
fibrosis 5 5.00 Very Low Very Low Very Low
Prostatitis 5 5.00 Very Low Very Low Very Low
agonist 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hypersensitivity 7 100.00 Very High Very High Very High
Hyperplasia 10 98.60 Very High Very High Very High
Frailty 5 95.04 Very High Very High Very High
Injury 26 91.24 High High
Trematode Infection 1 87.64 High High
Cholangiocarcinoma 5 86.12 High High
Overdose 2 83.32 Quite High
Pressure And Volume Under Development 6 83.04 Quite High
Hemorrhage 6 82.48 Quite High
Reperfusion Injury 58 81.36 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
When TP was over 3.7 mg/kg, the organ quotient, volume, area of prostate glandular cavity showed further increase which was obvious and AR express markedly, which support the fact that androgen is a crucial hormone for prostate development.[15]
Gene_expression (was) of TP in cavity
1) Confidence 0.43 Published 2010 Journal Indian Journal of Pharmacology Section Body Doc Link PMC2959216 Disease Relevance 0.31 Pain Relevance 0
Effect of different dosages of E2 with TP (3.7 mg/kg)
Gene_expression (Effect) of TP
2) Confidence 0.43 Published 2010 Journal Indian Journal of Pharmacology Section Body Doc Link PMC2959216 Disease Relevance 0 Pain Relevance 0
Effect of different dosages of E2 with TP (0.74 mg/kg)
Gene_expression (Effect) of TP
3) Confidence 0.43 Published 2010 Journal Indian Journal of Pharmacology Section Body Doc Link PMC2959216 Disease Relevance 0 Pain Relevance 0
Effect of different dosages of E2 with TP (92.6 mg/kg)
Gene_expression (Effect) of TP
4) Confidence 0.43 Published 2010 Journal Indian Journal of Pharmacology Section Body Doc Link PMC2959216 Disease Relevance 0 Pain Relevance 0
Effect of different dosages of E2 with TP (18.5 mg/kg)
Gene_expression (Effect) of TP
5) Confidence 0.43 Published 2010 Journal Indian Journal of Pharmacology Section Body Doc Link PMC2959216 Disease Relevance 0 Pain Relevance 0
In conclusion, our results indicate that both endogenous TXA2 production and hypersensitivity of the TP-receptors and/or the Rho-kinase signaling pathway in the cerebrovascular smooth muscle contribute to the development of CBF oscillations after NO synthase blockade.
Gene_expression (production) of TP in smooth muscle associated with hypersensitivity
6) Confidence 0.23 Published 2010 Journal PLoS ONE Section Body Doc Link PMC3013104 Disease Relevance 0.33 Pain Relevance 0.07
Our study found that the increased ratios of S/L, LDH and CK, and the decreased levels of TP in groups M, C and group K compared to group S in the survival rats.
Gene_expression (levels) of TP
7) Confidence 0.23 Published 2008 Journal BMC Gastroenterol Section Body Doc Link PMC2564972 Disease Relevance 1.25 Pain Relevance 0.25
Supernatants were transferred into fresh tubes for evaluation of concentration of glutamic-oxaloacetic transaminase (AST), glutamic pyruvic transaminase (ALT), the ratio of AST compare ALT (S/L), total protein (TP), albumin (ALB), globulin (GLB), the ratio of ALB compare GLB (A/G), phosphocreatine kinase (CK), lactate dehydrogenase (LDH), urea nitrogen (BUN) and creatinine (CRE) through automatic biochemistry analyzer(abbott, USA).


Gene_expression (compare) of TP in tubes
8) Confidence 0.20 Published 2008 Journal BMC Gastroenterol Section Body Doc Link PMC2564972 Disease Relevance 0.22 Pain Relevance 0.04
The expression levels of almost all target genes investigated including TP, DPD, ENT1, UNG1, TOP2A, BIRC5, TP73 and DeltaNp73 appeared to be significantly altered in these resistant strains.
Gene_expression (expression) of TP
9) Confidence 0.02 Published 2008 Journal Chemotherapy Section Body Doc Link 18714155 Disease Relevance 0.26 Pain Relevance 0

General Comments

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