INT154193

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Context Info
Confidence 0.22
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 3
Disease Relevance 0.48
Pain Relevance 0.74

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoskeleton (Mtap2) intracellular (Mtap2) plasma membrane (KCNK2)
protein complex (Mtap2) cytoplasm (Mtap2)
KCNK2 (Homo sapiens)
Mtap2 (Mus musculus)
Pain Link Frequency Relevance Heat
Neurotransmitter 3 94.56 High High
Pain 3 83.08 Quite High
anesthesia 3 82.84 Quite High
ischemia 3 82.04 Quite High
Disease Link Frequency Relevance Heat
Pain 3 83.08 Quite High
Cv Unclassified Under Development 3 82.04 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Mtap2 binding to TREK-1 and TREK-2 does not affect directly channel properties but enhances channel surface expression and current density.
TREK-1 Binding (binding) of Mtap2
1) Confidence 0.22 Published 2008 Journal J. Neurosci. Section Abstract Doc Link 18716213 Disease Relevance 0.17 Pain Relevance 0.25
Mtap2 binding to TREK-1 and TREK-2 does not affect directly channel properties but enhances channel surface expression and current density.
TREK-2 Binding (binding) of Mtap2
2) Confidence 0.22 Published 2008 Journal J. Neurosci. Section Abstract Doc Link 18716213 Disease Relevance 0.17 Pain Relevance 0.25
Mtap2 and AKAP150 interacting sites in TREK-1 are distinct and both proteins can dock simultaneously.
TREK-1 Binding (interacting) of Mtap2
3) Confidence 0.17 Published 2008 Journal J. Neurosci. Section Abstract Doc Link 18716213 Disease Relevance 0.15 Pain Relevance 0.23

General Comments

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