INT154235

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Context Info
Confidence 0.78
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.77
Pain Relevance 0.10

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

protein transporter activity (KPNA1) cytosol (KPNA1) nucleoplasm (KPNA1)
nucleus (KPNA1) cytoplasm (KPNA1)
KPNA1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Crohn's disease 3 98.12 Very High Very High Very High
rheumatoid arthritis 3 97.48 Very High Very High Very High
Multiple sclerosis 1 46.96 Quite Low
spinal inflammation 1 43.88 Quite Low
Pain 4 5.00 Very Low Very Low Very Low
Inflammation 2 5.00 Very Low Very Low Very Low
Pain management 1 5.00 Very Low Very Low Very Low
Paracetamol 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 86 98.86 Very High Very High Very High
Diabetes Mellitus 4 97.80 Very High Very High Very High
Rheumatoid Arthritis 3 97.48 Very High Very High Very High
Lymphatic Filariasis 89 78.08 Quite High
Chronic Disease 31 63.76 Quite High
Inflammatory Bowel Disease 1 53.44 Quite High
Autoimmune Disease 1 52.24 Quite High
Hypopigmentation 1 50.68 Quite High
Systemic Lupus Erythematosus 2 50.24 Quite High
Acute Disease 4 49.88 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We confirmed the validity of our findings by analyzing independent sets of most significant disease-linked SNPs and demonstrating statistically significant KPNA1-gene expression phenotypes associated with human genotypes of CD, BD, T2D and RA populations.
Gene_expression (expression) of KPNA1-gene associated with crohn's disease, diabetes mellitus, rheumatoid arthritis and disease
1) Confidence 0.78 Published 2008 Journal Cell Cycle Section Abstract Doc Link 18719369 Disease Relevance 1.43 Pain Relevance 0.10
Table 6 also shows that the infected patient sub-population groups (i.e. clinical and subclinical) have the greatest total lifetime benefits based on their larger proportion of the total benefit cohort population.
Gene_expression (proportion) of benefit cohort population
2) Confidence 0.03 Published 2010 Journal PLoS Neglected Tropical Diseases Section Body Doc Link PMC2879371 Disease Relevance 0.33 Pain Relevance 0

General Comments

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