INT154294

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Context Info
Confidence 0.69
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 3
Disease Relevance 3.09
Pain Relevance 0.41

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell adhesion (Nphs1) plasma membrane (Nphs1) protein complex (Nphs1)
Nphs1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
cINOD 6 80.32 Quite High
Disease Link Frequency Relevance Heat
Diabetes Mellitus 21 100.00 Very High Very High Very High
Albuminuria 3 81.20 Quite High
INFLAMMATION 6 80.08 Quite High
Proteinuria 3 78.12 Quite High
Injury 3 77.24 Quite High
Renal Disease 6 75.00 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The expression of nephrin and podocin protein was reduced in the glomeruli from diabetic rats, and MMF treatment significantly increased the expression of nephrin and podocin.
Positive_regulation (increased) of Gene_expression (expression) of nephrin associated with diabetes mellitus
1) Confidence 0.69 Published 2008 Journal Cytokine Section Abstract Doc Link 18725182 Disease Relevance 1.03 Pain Relevance 0.14
Our results show that MMF could decrease urinary albumin excretion, which mechanism may be at least partly correlated with upregulated expression of nephrin and podocin in the glomeruli of diabetic rat.
Positive_regulation (upregulated) of Gene_expression (expression) of nephrin associated with diabetes mellitus
2) Confidence 0.69 Published 2008 Journal Cytokine Section Abstract Doc Link 18725182 Disease Relevance 0.98 Pain Relevance 0.12
The expression of nephrin and podocin protein was reduced in the glomeruli from diabetic rats, and MMF treatment significantly increased the expression of nephrin and podocin.
Positive_regulation (increased) of Gene_expression (expression) of nephrin associated with diabetes mellitus
3) Confidence 0.50 Published 2008 Journal Cytokine Section Abstract Doc Link 18725182 Disease Relevance 1.08 Pain Relevance 0.15

General Comments

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