INT154340

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Context Info
Confidence 0.02
First Reported 2007
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 0.82
Pain Relevance 0.14

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (IGLL1)
Anatomy Link Frequency
central nervous system 1
IGLL1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Central nervous system 2 100.00 Very High Very High Very High
Opioid 1 86.80 High High
rheumatoid arthritis 11 50.00 Quite Low
cytokine 2 24.92 Low Low
corticosteroid 8 18.48 Low Low
withdrawal 3 5.00 Very Low Very Low Very Low
Antihistamine 3 5.00 Very Low Very Low Very Low
tolerance 3 5.00 Very Low Very Low Very Low
methotrexate 2 5.00 Very Low Very Low Very Low
Paracetamol 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Infection 14 100.00 Very High Very High Very High
Adhesions 4 91.36 High High
Rheumatoid Arthritis 25 88.48 High High
Death 1 86.48 High High
Lymphatic System Cancer 16 67.28 Quite High
Disease 31 25.44 Quite Low
Alopecia 1 16.56 Low Low
Vomiting 5 16.12 Low Low
Bladder Cancer 1 13.00 Low Low
Reprotox - General 1 1 11.52 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Importantly, there was no association between the incidence of serious infection and the presence of low Ig (including Ig isotypes).
Ig Neg (no) Binding (association) of associated with infection
1) Confidence 0.02 Published 2010 Journal Rheumatology (Oxford, England) Section Body Doc Link PMC2919195 Disease Relevance 0.44 Pain Relevance 0
Epratuzumab has been found to compete with the RFB4 antibody, which binds to the third Ig domain (Stein et al 1993).
Ig Binding (binds) of
2) Confidence 0.01 Published 2007 Journal Therapeutics and Clinical Risk Management Section Body Doc Link PMC2376077 Disease Relevance 0.20 Pain Relevance 0
Although their glycosylations are supposed to be associated with the development of the central nervous system like other Ig superfamily proteins, they are still unknown because of difficulty in isolating individual proteins with a high degree of homology in performing carbohydrate analysis.
Ig Binding (associated) of in central nervous system associated with central nervous system
3) Confidence 0.01 Published 2008 Journal Biochemistry Section Abstract Doc Link 18729387 Disease Relevance 0.18 Pain Relevance 0.14

General Comments

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