INT154361

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Context Info
Confidence 0.76
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.26
Pain Relevance 0.40

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Pam) lyase activity (Pam)
Anatomy Link Frequency
trigeminal ganglion 1
Pam (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Trigeminal ganglion neurons 10 100.00 Very High Very High Very High
Glutamate receptor 1 97.60 Very High Very High Very High
Spinal cord 1 89.76 High High
Neuropeptide 6 87.56 High High
IPN 1 86.00 High High
imagery 13 74.24 Quite High
calcitonin gene related peptide 8 62.08 Quite High
substance P 6 61.36 Quite High
Nerve growth factor 6 56.72 Quite High
Inflammation 1 36.72 Quite Low
Disease Link Frequency Relevance Heat
Ganglion Cysts 15 100.00 Very High Very High Very High
Inflammatory Pain 1 86.00 High High
Nociception 4 75.00 Quite High
Increased Venous Pressure Under Development 1 48.88 Quite Low
INFLAMMATION 2 36.72 Quite Low
Pain 1 5.00 Very Low Very Low Very Low
Natriuresis 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We detected an intermittent colocalization of PAM and ubiquitin with TSC2, a known substrate of PAM, and the glutamate receptors mGluR5 and GLUR1.
Localization (colocalization) of PAM associated with glutamate receptor
1) Confidence 0.76 Published 2008 Journal Mol. Cell Proteomics Section Abstract Doc Link 18753128 Disease Relevance 0.16 Pain Relevance 0.22
Our findings that LDCVs containing PAM-GFP or PHM-pHluorin undergo fusion along axons as well as at growth cone/endings in trigeminal ganglion neurons are consistent with a role for non-synaptic peptide release.
Localization (release) of PAM-GFP in trigeminal ganglion associated with ganglion cysts and trigeminal ganglion neurons
2) Confidence 0.13 Published 2010 Journal BMC Neurosci Section Body Doc Link PMC2838897 Disease Relevance 0.10 Pain Relevance 0.18

General Comments

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