INT154493

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Context Info
Confidence 0.45
First Reported 2004
Last Reported 2010
Negated 1
Speculated 0
Reported most in Title
Documents 3
Total Number 3
Disease Relevance 0.58
Pain Relevance 1.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (SRD5A1) small molecule metabolic process (SRD5A1) endoplasmic reticulum (SRD5A1)
cytoplasm (SRD5A1)
Anatomy Link Frequency
myometrium 2
SRD5A1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Pain 19 99.84 Very High Very High Very High
Morphine 53 99.48 Very High Very High Very High
Opioid 6 94.80 High High
Lasting pain 1 87.84 High High
Dismenorea 1 70.96 Quite High
Analgesic 3 67.08 Quite High
corticosteroid 2 5.00 Very Low Very Low Very Low
opiate 2 5.00 Very Low Very Low Very Low
Hippocampus 2 5.00 Very Low Very Low Very Low
opioid receptor 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pain 20 99.84 Very High Very High Very High
Breast Cancer 23 99.60 Very High Very High Very High
Cancer 68 74.92 Quite High
Dysmenorrhea 1 70.96 Quite High
Metastasis 4 9.76 Low Low
Carcinoma 8 5.00 Very Low Very Low Very Low
Adhesions 3 5.00 Very Low Very Low Very Low
Cognitive Disorder 3 5.00 Very Low Very Low Very Low
Stress 2 5.00 Very Low Very Low Very Low
Anaemia 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Regardless of labor status, there was no difference in SRD5A1 mRNA expression in the myometrium.
Neg (no) Regulation (difference) of Gene_expression (expression) of SRD5A1 mRNA in myometrium
1) Confidence 0.45 Published 2008 Journal Am J Perinatol Section Abstract Doc Link 18770491 Disease Relevance 0.07 Pain Relevance 0.07
Expression of progesterone metabolizing enzyme genes (AKR1C1, AKR1C2, AKR1C3, SRD5A1, SRD5A2) is altered in human breast carcinoma

Background

Regulation (altered) of Gene_expression (Expression) of SRD5A1 associated with breast cancer
2) Confidence 0.43 Published 2004 Journal BMC Cancer Section Title Doc Link PMC459223 Disease Relevance 0.32 Pain Relevance 0
Aromatase and 5-alpha reductase gene expression: modulation by pain and morphine treatment in male rats

Background

Regulation (modulation) of Gene_expression (expression) of 5-alpha reductase associated with pain and morphine
3) Confidence 0.26 Published 2010 Journal Mol Pain Section Title Doc Link PMC2978140 Disease Relevance 0.19 Pain Relevance 0.95

General Comments

This test has worked.

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