INT154553

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Context Info
Confidence 0.45
First Reported 2007
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 2.76
Pain Relevance 0.29

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (RHOH) mitochondrion (RHOH) plasma membrane (RHOH)
intracellular (RHOH) cytoplasm (RHOH)
Anatomy Link Frequency
superior 1
RHOH (Homo sapiens)
Pain Link Frequency Relevance Heat
Angina 2 83.60 Quite High
medulla 2 82.84 Quite High
Potency 1 80.72 Quite High
palliative 1 5.00 Very Low Very Low Very Low
agonist 1 5.00 Very Low Very Low Very Low
withdrawal 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hodgkin's Disease 2 93.84 High High
Diffuse Large B-cell Lymphoma 4 91.84 High High
Sclerosis 2 91.60 High High
Lymphatic System Cancer 8 85.52 High High
Cough 2 84.16 Quite High
Angina 2 83.60 Quite High
Dyspnea 2 82.64 Quite High
Superior Vena Cava Syndrome 2 81.60 Quite High
Advanced Or Metastatic Breast Cancer 20 78.32 Quite High
Weight Gain 1 77.60 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Its main molecular characteristics include: gains in 9p segments, p53 mutations, BCL-2 and MAL gene over-expression, somatic mutations of IgVH genes, BCL-6, PIM-1, PAX-5, RhoH/TTF, and c-MYC, and constitutional NF-kappaB activation.
Positive_regulation (activation) of TTF
1) Confidence 0.45 Published 2008 Journal Crit. Rev. Oncol. Hematol. Section Abstract Doc Link 18774728 Disease Relevance 1.30 Pain Relevance 0.12
Its main molecular characteristics include: gains in 9p segments, p53 mutations, BCL-2 and MAL gene over-expression, somatic mutations of IgVH genes, BCL-6, PIM-1, PAX-5, RhoH/TTF, and c-MYC, and constitutional NF-kappaB activation.
Positive_regulation (activation) of RhoH
2) Confidence 0.45 Published 2008 Journal Crit. Rev. Oncol. Hematol. Section Abstract Doc Link 18774728 Disease Relevance 1.30 Pain Relevance 0.13
Letrozole 2.5 mg was also significantly superior in TTP, TTF, and overall survival (OS).
Positive_regulation (superior) of TTF in superior
3) Confidence 0.18 Published 2007 Journal Breast Cancer Res Treat Section Body Doc Link PMC2001219 Disease Relevance 0.16 Pain Relevance 0.04

General Comments

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