INT154554

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Context Info
Confidence 0.75
First Reported 2008
Last Reported 2008
Negated 1
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 3.26
Pain Relevance 0.24

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (RHOH) mitochondrion (RHOH) plasma membrane (RHOH)
intracellular (RHOH) cytoplasm (RHOH)
RHOH (Homo sapiens)
Pain Link Frequency Relevance Heat
medulla 2 85.68 High High
Angina 2 79.44 Quite High
fibrosis 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 24 95.24 Very High Very High Very High
Sclerosis 2 94.44 High High
Hodgkin's Disease 2 89.68 High High
Diffuse Large B-cell Lymphoma 4 88.64 High High
Lymphatic System Cancer 8 88.36 High High
Cough 2 80.00 Quite High
Angina 2 79.44 Quite High
Dyspnea 2 78.48 Quite High
Superior Vena Cava Syndrome 2 77.44 Quite High
Rhinitis 3 76.76 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Its main molecular characteristics include: gains in 9p segments, p53 mutations, BCL-2 and MAL gene over-expression, somatic mutations of IgVH genes, BCL-6, PIM-1, PAX-5, RhoH/TTF, and c-MYC, and constitutional NF-kappaB activation.
Gene_expression (over-expression) of TTF
1) Confidence 0.75 Published 2008 Journal Crit. Rev. Oncol. Hematol. Section Abstract Doc Link 18774728 Disease Relevance 1.27 Pain Relevance 0.12
Its main molecular characteristics include: gains in 9p segments, p53 mutations, BCL-2 and MAL gene over-expression, somatic mutations of IgVH genes, BCL-6, PIM-1, PAX-5, RhoH/TTF, and c-MYC, and constitutional NF-kappaB activation.
Gene_expression (over-expression) of RhoH
2) Confidence 0.75 Published 2008 Journal Crit. Rev. Oncol. Hematol. Section Abstract Doc Link 18774728 Disease Relevance 1.27 Pain Relevance 0.12
Tumor cells showed diffuse immunopositivity for calcitonin, HMB-45, carcinoembryonic antigen, synaptophysin, chromogranin, vimentin and epithelial membrane antigen but focal paranuclear dot-like positivity for cytokeratin (Fig 2a–f), and were negative for thyroglobulin, S-100, melan-A and TTF (Table 2).
Neg (negative) Gene_expression (negative) of TTF associated with cancer
3) Confidence 0.01 Published 2008 Journal Diagn Pathol Section Body Doc Link PMC2253502 Disease Relevance 0.72 Pain Relevance 0

General Comments

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