INT154593

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Context Info
Confidence 0.06
First Reported 2008
Last Reported 2008
Negated 1
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.06
Pain Relevance 0.19

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Ntrk2) endosome (Ntrk2) aging (Ntrk2)
plasma membrane (Ntrk2) transmembrane transport (Kcna3)
Ntrk2 (Rattus norvegicus)
Kcna3 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
tetrodotoxin 1 87.36 High High
Glutamate receptor 1 83.96 Quite High
Action potential 1 59.92 Quite High
potassium channel 1 55.32 Quite High
GABAergic 1 45.72 Quite Low
Disease Link Frequency Relevance Heat
Targeted Disruption 1 64.16 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Kv3 protein levels were not changed by exogenous tropomyosin-related kinase B (TrkB) ligands, but the levels decreased upon inhibiting the MAPK signaling suggesting a role for endogenous factors and in particular MEK2 signaling for translation.
TrkB Neg (not) Regulation (changed) of Kv3
1) Confidence 0.06 Published 2008 Journal Neuroscience Section Abstract Doc Link 18775767 Disease Relevance 0.06 Pain Relevance 0.19

General Comments

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