INT154678

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Context Info
Confidence 0.49
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.70
Pain Relevance 0.12

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (TAT) mitochondrion (TAT) small molecule metabolic process (TAT)
biosynthetic process (TAT) cellular nitrogen compound metabolic process (TAT) cellular_component (TAT)
Anatomy Link Frequency
monocyte 2
TAT (Homo sapiens)
Pain Link Frequency Relevance Heat
anesthesia 1 92.56 High High
Inflammation 2 64.56 Quite High
metalloproteinase 1 33.00 Quite Low
chemokine 5 5.00 Very Low Very Low Very Low
corticosteroid 3 5.00 Very Low Very Low Very Low
cytokine 2 5.00 Very Low Very Low Very Low
Spinal cord 1 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
abdominal pain 1 5.00 Very Low Very Low Very Low
rheumatoid arthritis 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Adhesions 2 100.00 Very High Very High Very High
Acquired Immune Deficiency Syndrome Or Hiv Infection 15 96.40 Very High Very High Very High
Epstein-barr Virus 30 95.20 Very High Very High Very High
Diffuse Large B-cell Lymphoma 56 94.64 High High
Cancer 41 88.16 High High
Aggression 1 86.24 High High
Lymphatic System Cancer 122 84.24 Quite High
Heart Rate Under Development 1 76.56 Quite High
INFLAMMATION 2 64.56 Quite High
B-cell Lymphoma 27 38.36 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
When compared to standard CPB, the Synergy showed lower levels of the monocyte-platelet adhesion index at T2 (0.023 +/- 0.005 vs 0.063 +/- 0.013, P = 0.0092) and T4 (0.031 +/- 0.003 vs 0.055 +/- 0.005, P = 0.0017), TAT complexes at T2 (27.175 +/- 5.967 vs 86.592 +/- 5.415, P = 0.0005) and T3 (26.977 +/- 2.468 vs 45.146 +/- 4.365, P = 0.0041), F1+2 fragments at T2 (2.222 +/- 0.226 vs 4.249 +/- 0.292, P = 0.0009), and sP-selectin at T3 (115.17 +/- 19.623 vs 169.554 +/- 19.709, P = 0.0703) and T4 (108.542 +/- 6.429 vs 140.799 +/- 14.771, P = 0.0833).
Positive_regulation (showed) of Gene_expression (levels) of TAT in monocyte associated with adhesions
1) Confidence 0.49 Published 2008 Journal Perfusion Section Abstract Doc Link 18788218 Disease Relevance 0.32 Pain Relevance 0.12
VEGF promoter activity was downregulated in vitro in cells transfected with Tat.
Positive_regulation (transfected) of Gene_expression (transfected) of Tat
2) Confidence 0.49 Published 2008 Journal J Hematop Section Body Doc Link PMC2713479 Disease Relevance 1.38 Pain Relevance 0

General Comments

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