INT154706
From wiki-pain
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Sentences Mentioned In
Key: | Protein | Mutation | Event | Anatomy | Negation | Speculation | Pain term | Disease term |
A subsequent whole body scan and serum thyroglobulin determination were negative. | |||||||||||||||
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Immunohistochemistry showed pancytokeratin positivity while thyroglobulin and calcitonin were negative. | |||||||||||||||
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This PS1-PLD1 interaction recruits PLD1 to the Golgi/TGN and thus potentially alters APP trafficking as PLD1 overexpression promotes budding of vesicles from the TGN containing APP and increases cell surface levels of APP [176,177]. | |||||||||||||||
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The cleavage of various substrates appears to be dependent on the subcellular compartment; APP is mainly cleaved in the TGN and early endosomal domains whereas Notch is primarily cleaved at the plasma membrane [34,36,123]. | |||||||||||||||
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The ANOVA comparing COG distances A versus B were not significant between hemispheres or sessions (Table 3). | |||||||||||||||
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Furthermore, the virus that was shown to persist mainly in the thyroid epithelial cells in which thyroglobulin is synthesized induced a reduction in the level of thyroglobulin messenger RNA and circulating thyroid hormones, but there was no thyroid cell destruction. | |||||||||||||||
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-secretase complex were found to co-reside in lipid raft microdomains with VAMP-4 (TGN), syntaxin 6 (TGN vesicles) and syntaxin 13 (late endosomes). | |||||||||||||||
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Examples of tissue specific patterns are those of MUC1, CEA, PSA, thyroglobulin, and calcitonin whereas tumour selective patterns include HER2 FGFR4 and VEGF [97]. | |||||||||||||||
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Although, there were no statistical differences in IL-2 mRNA and IL-10 m RNA expressions between G93A mice treated with different cell doses and control animals (Media, CsA, hTgn, C57), mice receiving 25×106 MNC hUCB cells tended towards decreased IL-2 mRNA and increased IL-10 mRNA expressions in the spleen. | |||||||||||||||
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mRNA expression in the brainstem between cell-treated and non-treated G93A mice; all showing high cytokine expression vs. control hTgn or C57BL/6 mice: Media (p<0.01), CsA (p<0.001), MNC hUCB 10×106 (p<0.05), MNC hUCB 25×106 (p<0.05), and MNC hUCB 50×106 (p<0.01). | |||||||||||||||
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