INT154728

Context Info Confidence 0.42 First Reported 2009 Last Reported 2009 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 1 Disease Relevance 0 Pain Relevance 0.59

endoplasmic reticulum (Cyp2b1)

Cyp2b1 (Rattus norvegicus)

Pain Link Frequency Relevance Heat Paracetamol 8 99.88

Disease Link Frequency Relevance Heat Toxicity 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

The administration of ACET down-regulated CYP1A2 and CYP2B1 expression in CD rats, while up-regulating them in NF rats.

Regulation (regulated) of Gene_expression (expression) of CYP2B1 associated with paracetamol

1) Confidence 0.42 Published 2009 Journal J Appl Toxicol Section Abstract Doc Link 18798224 Disease Relevance 0 Pain Relevance 0.59

General Comments

This test has worked.