INT154766

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Context Info
Confidence 0.47
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.45
Pain Relevance 0.66

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Nox1, Prkce) plasma membrane (Nox1, Prkce) endosome (Nox1)
mitochondrion (Prkce) transport (Nox1) endoplasmic reticulum (Prkce)
Anatomy Link Frequency
DRG 2
Nox1 (Mus musculus)
Prkce (Mus musculus)
Pain Link Frequency Relevance Heat
Pain 5 96.92 Very High Very High Very High
qutenza 1 80.40 Quite High
Serotonin 1 77.76 Quite High
bradykinin 1 77.32 Quite High
IPN 1 75.00 Quite High
Hyperalgesia 3 68.68 Quite High
Inflammation 3 56.68 Quite High
nociceptor 2 25.00 Low Low
Disease Link Frequency Relevance Heat
Inflammatory Pain 1 75.00 Quite High
Nociception 1 71.20 Quite High
Hyperalgesia 3 68.68 Quite High
Pain 1 59.00 Quite High
INFLAMMATION 1 56.68 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These findings indicate that NOX1/NADPH oxidase accelerates the translocation of PKCepsilon in DRG neurons, thereby enhancing the TRPV1 activity and the sensitivity to painful stimuli.
NOX1 Positive_regulation (accelerates) of Localization (translocation) of PKCepsilon in DRG associated with pain
1) Confidence 0.47 Published 2008 Journal J. Neurosci. Section Abstract Doc Link 18799680 Disease Relevance 0.45 Pain Relevance 0.66

General Comments

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