INT154803

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Context Info
Confidence 0.33
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.84
Pain Relevance 0.12

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (EGR1) intracellular (EGR1) DNA binding (EGR1)
cell-cell signaling (GDF15) cytoplasm (EGR1) extracellular space (GDF15)
EGR1 (Homo sapiens)
GDF15 (Homo sapiens)
Pain Link Frequency Relevance Heat
cINOD 1 83.16 Quite High
Inflammation 2 82.68 Quite High
Disease Link Frequency Relevance Heat
Apoptosis 6 99.36 Very High Very High Very High
Shock 1 95.52 Very High Very High Very High
INFLAMMATION 2 82.68 Quite High
Leukemia 1 75.00 Quite High
Death 1 54.48 Quite High
Cancer 2 54.04 Quite High
Disease 1 39.12 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Although further studies are needed to demonstrate that increased expression of Egr-1 by platycodon D leads directly to NAG-1 induction and subsequent apoptosis, our observations clearly indicate that ROS induced through Egr-1 activation are involved in the early molecular events involved in the platycodon D-induced apoptotic pathway.
Gene_expression (expression) of Egr-1 Positive_regulation (leads) of Positive_regulation (induction) of NAG-1 associated with apoptosis
1) Confidence 0.33 Published 2009 Journal Biomed. Pharmacother. Section Abstract Doc Link 18804340 Disease Relevance 0.84 Pain Relevance 0.12

General Comments

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