INT154868

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Context Info
Confidence 0.35
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 1.01
Pain Relevance 0.36

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Hrh4) plasma membrane (Hrh4) signal transducer activity (Hrh4)
Hrh4 (Mus musculus)
Pain Link Frequency Relevance Heat
antagonist 41 91.52 High High
Potency 1 89.92 High High
Inflammation 38 87.08 High High
cytokine 30 69.96 Quite High
Serotonin 2 60.00 Quite High
Antinociceptive 1 34.96 Quite Low
Pain 2 32.56 Quite Low
chemokine 5 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Antihistamine 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hypersensitivity 11 98.44 Very High Very High Very High
Asthma 43 93.36 High High
INFLAMMATION 34 87.08 High High
Hyperplasia 13 80.12 Quite High
Airway Remodeling 2 23.60 Low Low
Disease 2 15.24 Low Low
Pneumonia 4 5.00 Very Low Very Low Very Low
Rhinitis 3 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Fibrosis 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The H4R and IL-13 also both appear to mediate allergic airway dysfunction.
H4R Binding (The) of associated with hypersensitivity
1) Confidence 0.35 Published 2010 Journal Respir Res Section Body Doc Link PMC2914735 Disease Relevance 1.01 Pain Relevance 0.32
A series of 2-aminopyrimidines was synthesized as ligands of the histamine H4 receptor (H4R).
H4R Binding (ligands) of
2) Confidence 0.09 Published 2008 Journal J. Med. Chem. Section Abstract Doc Link 18811133 Disease Relevance 0 Pain Relevance 0.04

General Comments

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