INT154877

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Context Info
Confidence 0.19
First Reported 2008
Last Reported 2009
Negated 0
Speculated 1
Reported most in Body
Documents 3
Total Number 4
Disease Relevance 2.73
Pain Relevance 0.78

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

intracellular (LGALS1) cytoplasm (LGALS1) signal transducer activity (LGALS1)
extracellular space (LGALS1) signal transduction (LGALS1) extracellular region (LGALS1)
Anatomy Link Frequency
immune system 2
HbL 1
LGALS1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 75 92.32 High High
Thalamus 1 83.88 Quite High
Inflammatory response 2 83.20 Quite High
Pain 1 73.12 Quite High
cytokine 58 67.08 Quite High
Crohn's disease 8 5.00 Very Low Very Low Very Low
chemokine 5 5.00 Very Low Very Low Very Low
Adalimumab 4 5.00 Very Low Very Low Very Low
corticosteroid 3 5.00 Very Low Very Low Very Low
abdominal pain 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Dyskinesias 1 99.76 Very High Very High Very High
Colitis 34 99.36 Very High Very High Very High
Hodgkin's Disease 25 99.28 Very High Very High Very High
Movement Disorders 2 95.60 Very High Very High Very High
Nociception 2 95.36 Very High Very High Very High
INFLAMMATION 55 92.32 High High
Mucositis 20 88.56 High High
Lymphatic System Cancer 122 83.28 Quite High
Pain 1 73.12 Quite High
Diffuse Large B-cell Lymphoma 56 68.72 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The interaction between CM-Pf, HbL, GPi, STN and SNC might provide a new template for high frequency stimulation strategies in the treatment of movement disorders.
HbL Spec (might) Binding (interaction) of in HbL associated with movement disorders
1) Confidence 0.19 Published 2009 Journal Brain Res. Bull. Section Abstract Doc Link 18812212 Disease Relevance 0.52 Pain Relevance 0.12
Galectin-1 (Gal1) is an immunomodulatory glycan-binding protein regulated by an AP1-dependent enhancer in HRS cells and its expression affects the microenvironment in HL.
Gal1 Binding (binding) of associated with hodgkin's disease
2) Confidence 0.06 Published 2008 Journal J Hematop Section Body Doc Link PMC2713479 Disease Relevance 1.10 Pain Relevance 0.03
However, Gal-1 is constitutively expressed in most organs [5], showing that Gal-1 broadly, but also nonspecifically, interact with the immune system.
Gal-1 Binding (interact) of in immune system
3) Confidence 0.05 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2440804 Disease Relevance 0.54 Pain Relevance 0.31
However, Gal-1 is constitutively expressed in most organs [5], showing that Gal-1 broadly, but also nonspecifically, interact with the immune system.
Gal-1 Binding (interact) of in immune system
4) Confidence 0.03 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2440804 Disease Relevance 0.56 Pain Relevance 0.32

General Comments

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