INT154963

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Context Info
Confidence 0.15
First Reported 2008
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.76
Pain Relevance 0.14

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (Il17rb) plasma membrane (Il17rb) cytoplasm (Il17rb)
Anatomy Link Frequency
T cells 1
Il17rb (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 45 90.40 High High
Inflammation 27 81.44 Quite High
Pain 4 50.00 Quite Low
Arthritis 4 50.00 Quite Low
chemokine 6 5.00 Very Low Very Low Very Low
fibrosis 3 5.00 Very Low Very Low Very Low
tolerance 3 5.00 Very Low Very Low Very Low
Neuritis 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
Multiple sclerosis 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Asthma 104 84.32 Quite High
INFLAMMATION 28 81.44 Quite High
Arthritis 4 81.28 Quite High
Hypersensitivity 24 80.64 Quite High
Pain 2 79.48 Quite High
Hyperplasia 4 69.00 Quite High
Disease 14 62.32 Quite High
Eosinophilia 8 53.96 Quite High
Targeted Disruption 6 51.76 Quite High
Arthralgia 1 50.00 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The effects of IL-1RI receptor inhibition in GFAP-IL-1betaXAT mice were studied in the GFAP-IL-1betaXAT-IL-1RI(-/-) compound mouse model.
Neg (inhibition) Gene_expression (inhibition) of IL-1RI receptor
1) Confidence 0.15 Published 2008 Journal Arthritis Rheum. Section Body Doc Link 18821694 Disease Relevance 0.16 Pain Relevance 0
While these cells exhibit the characteristics of a typical accessory cell type, most recently a subset of invariant natural killer T cells (iNKT cells) expressing IL-17RB, a receptor for IL-25, have also been identified as a target for IL-25.
Gene_expression (expressing) of IL-17RB in T cells
2) Confidence 0.03 Published 2010 Journal Journal of Allergy Section Body Doc Link PMC2957587 Disease Relevance 0.60 Pain Relevance 0.14

General Comments

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