INT155007

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.27
First Reported 2007
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 4
Total Number 6
Disease Relevance 9.17
Pain Relevance 1.30

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (RETN) extracellular region (RETN) nucleus (RETN)
biological_process (RETN)
Anatomy Link Frequency
adipocytes 4
monocytes 2
neurons 2
SK-N-SH 2
RETN (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 99 100.00 Very High Very High Very High
Inflammatory mediators 6 100.00 Very High Very High Very High
cytokine 177 99.96 Very High Very High Very High
Chronic pancreatitis 3 99.28 Very High Very High Very High
fibrosis 1 97.24 Very High Very High Very High
Inflammatory response 1 95.16 Very High Very High Very High
Inflammatory marker 3 67.48 Quite High
Central nervous system 20 5.00 Very Low Very Low Very Low
chemokine 16 5.00 Very Low Very Low Very Low
Multiple sclerosis 8 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 116 100.00 Very High Very High Very High
Obesity 91 100.00 Very High Very High Very High
Viral Meningitis 14 99.56 Very High Very High Very High
Drug Induced Neurotoxicity 4 99.32 Very High Very High Very High
Pancreatitis 3 99.28 Very High Very High Very High
Diabetes Mellitus 78 99.02 Very High Very High Very High
Death 76 97.28 Very High Very High Very High
Fibrosis 1 97.24 Very High Very High Very High
Apoptosis 28 97.00 Very High Very High Very High
Polycystic Ovary Syndrome 166 96.08 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Resistin is implicated in the pathogenesis of Type 2 diabetes and obesity (Seow et al 2004) where circulating resistin levels and resistin expression in adipocytes are increased.
Positive_regulation (increased) of Gene_expression (expression) of resistin in adipocytes associated with diabetes mellitus and obesity
1) Confidence 0.27 Published 2007 Journal Vascular Health and Risk Management Section Body Doc Link PMC1994046 Disease Relevance 1.99 Pain Relevance 0.07
Early investigations into the role of resistin as an inflammatory factor demonstrated that LPS (lipopolysaccharide) up-regulated resistin expression in rat WAT, 3T3-L1 adipocytes and human monocytes [16].
Positive_regulation (regulated) of Gene_expression (expression) of resistin in monocytes associated with inflammation and obesity
2) Confidence 0.22 Published 2010 Journal Cardiovasc Diabetol Section Body Doc Link PMC2946274 Disease Relevance 2.06 Pain Relevance 0.27
Increased serum resistin concentration in patients with chronic pancreatitis: possible cause of pancreatic fibrosis.
Spec (possible) Positive_regulation (Increased) of Gene_expression (concentration) of resistin associated with fibrosis and chronic pancreatitis
3) Confidence 0.22 Published 2009 Journal J. Clin. Gastroenterol. Section Title Doc Link 18827713 Disease Relevance 0.20 Pain Relevance 0.33
Resistin is implicated in the pathogenesis of Type 2 diabetes and obesity (Seow et al 2004) where circulating resistin levels and resistin expression in adipocytes are increased.
Positive_regulation (increased) of Gene_expression (expression) of resistin in adipocytes associated with diabetes mellitus and obesity
4) Confidence 0.19 Published 2007 Journal Vascular Health and Risk Management Section Body Doc Link PMC1994046 Disease Relevance 2.05 Pain Relevance 0.07
WNV-associated encephalitis (WNVE) is characterized by increased production of pro-inflammatory mediators, glial cells activation and eventual loss of neurons.
Positive_regulation (increased) of Gene_expression (production) of pro-inflammatory in neurons associated with inflammatory mediators and viral meningitis
5) Confidence 0.01 Published 2010 Journal J Neuroinflammation Section Abstract Doc Link PMC2984415 Disease Relevance 1.03 Pain Relevance 0.24
WNV induces expression of multiple pro-inflammatory cytokines in human neuroblastome cell line, SK-N-SH
Positive_regulation (induces) of Gene_expression (expression) of pro-inflammatory in SK-N-SH associated with inflammation and cytokine
6) Confidence 0.01 Published 2010 Journal J Neuroinflammation Section Body Doc Link PMC2984415 Disease Relevance 1.84 Pain Relevance 0.33

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox