INT155086

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Context Info
Confidence 0.21
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 1.26
Pain Relevance 0.45

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (CASP1, DAXX) cytosol (CASP1, DAXX) nucleoplasm (DAXX)
intracellular (CASP1) enzyme binding (DAXX) signal transduction (CASP1)
CASP1 (Homo sapiens)
DAXX (Homo sapiens)
Pain Link Frequency Relevance Heat
methadone 1 80.92 Quite High
opiate 7 75.00 Quite High
addiction 2 65.24 Quite High
tolerance 2 64.64 Quite High
Disease Link Frequency Relevance Heat
Death 5 100.00 Very High Very High Very High
Apoptosis 9 93.28 High High
Leukemia 1 76.00 Quite High
Recurrence 2 67.76 Quite High
Opiate Addiction 1 62.16 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The initiator caspase-8 was not altered, but FLIP(L) (Fas-associated protein with death domain-like interleukin-1beta-converting enzyme-inhibitory protein), a dominant inhibitor of caspase-8, was increased in LT addicts (19%).
interleukin-1beta-converting enzyme Negative_regulation (inhibitor) of Fas-associated protein associated with death
1) Confidence 0.21 Published 2008 Journal Neuroscience Section Abstract Doc Link 18834930 Disease Relevance 1.26 Pain Relevance 0.45

General Comments

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