INT155150

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Context Info
Confidence 0.26
First Reported 2006
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 5
Total Number 5
Disease Relevance 1.21
Pain Relevance 0.86

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Spic) DNA binding (Spic)
Anatomy Link Frequency
DRG 2
neural 1
Spic (Mus musculus)
Pain Link Frequency Relevance Heat
postherpetic neuralgia 10 100.00 Very High Very High Very High
dorsal root ganglion 6 100.00 Very High Very High Very High
Pain 2 97.60 Very High Very High Very High
Intractable pain 2 92.12 High High
Inflammation 6 82.16 Quite High
cytokine 12 16.80 Low Low
cINOD 5 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Post Operative Pain 10 100.00 Very High Very High Very High
Ganglion Cysts 6 100.00 Very High Very High Very High
Pain 2 97.60 Very High Very High Very High
Intractable Pain 2 92.12 High High
INFLAMMATION 7 82.16 Quite High
Poisoning 4 5.00 Very Low Very Low Very Low
Hypertension 3 5.00 Very Low Very Low Very Low
Helminth Infection 2 5.00 Very Low Very Low Very Low
Alopecia 2 5.00 Very Low Very Low Very Low
Congenital Anomalies 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
CONCLUSIONS: PRF lesioning of DRG showed significant pain relief compared with the conventional treatments in patients with intractable PHN.
Gene_expression (lesioning) of PRF in DRG
1) Confidence 0.26 Published 2008 Journal Acta Anaesthesiol Scand Section Body Doc Link 18840116 Disease Relevance 0.13 Pain Relevance 0
We assessed the efficacy of PRF lesioning of DRG for PHN via an open, nonrandomized study.
Gene_expression (lesioning) of PRF in DRG associated with dorsal root ganglion and postherpetic neuralgia
2) Confidence 0.26 Published 2008 Journal Acta Anaesthesiol Scand Section Abstract Doc Link 18840116 Disease Relevance 0.94 Pain Relevance 0.79
Using the data from the whole pheromone study (618% labeling above background) and the data from the two present studies, we find that PRF and PMF together (330% + 124% = 454% labeling above background) produce neural labeling that is 73.5% of that produced by whole pheromone (454% / 618% = 73.5%).
Gene_expression (produce) of PRF in neural
3) Confidence 0.16 Published 2006 Journal BMC Neurosci Section Body Doc Link PMC1550415 Disease Relevance 0 Pain Relevance 0
When expressed as a percentage of control numbers, whole pheromone (containing both PRF and PMF) produced labeling 618% above control levels while PRF produced 330% labeling and PMF produced 124% labeling above the respective control group levels.
Gene_expression (produced) of PRF
4) Confidence 0.13 Published 2006 Journal BMC Neurosci Section Body Doc Link PMC1550415 Disease Relevance 0 Pain Relevance 0
As our sample was unselected and PRFs are widely consumed during pregnancy, the larger number of patients in the 75th percentile of PRF intake expresses the high PRF consumption pattern in our population.
Gene_expression (expresses) of PRF
5) Confidence 0.09 Published 2010 Journal J Perinatol Section Body Doc Link PMC2834346 Disease Relevance 0.15 Pain Relevance 0.07

General Comments

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