INT155158

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Context Info
Confidence 0.00
First Reported 2008
Last Reported 2008
Negated 1
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.10
Pain Relevance 0.22

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Agtr2, Rtn4) nuclear envelope (Rtn4) aging (Rtn4)
endoplasmic reticulum (Rtn4) protein complex (Rtn4) cytoplasm (Rtn4)
Anatomy Link Frequency
neurons 1
Agtr2 (Rattus norvegicus)
Rtn4 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Root ganglion neuron 1 99.16 Very High Very High Very High
tetrodotoxin 1 96.24 Very High Very High Very High
sodium channel 2 75.00 Quite High
Disease Link Frequency Relevance Heat
Ganglion Cysts 1 98.96 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In addition, JZTX-II had no effect on TTX-R VGSCs on rat dorsal root ganglion neurons but exerted a concentration-dependent reduction in tetrodotoxin-sensitive (TTX-S) VGSCs accompanied by a slowing of sodium current inactivation similar to delta-ACTXs.
JZTX-II Neg (no) Regulation (effect) of TTX-R in neurons associated with ganglion cysts, tetrodotoxin and root ganglion neuron
1) Confidence 0.00 Published 2008 Journal Biochem. Pharmacol. Section Abstract Doc Link 18840410 Disease Relevance 0.10 Pain Relevance 0.22

General Comments

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