INT155174

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Context Info
Confidence 0.24
First Reported 2003
Last Reported 2008
Negated 1
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 1.57
Pain Relevance 0.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (HIF1A) signal transduction (HIF1A) nucleolus (HIF1A)
nucleus (HIF1A) transcription factor binding (HIF1A) cytoplasm (HIF1A)
HIF1A (Homo sapiens)
Pain Link Frequency Relevance Heat
Central nervous system 1 82.56 Quite High
Angina 3 50.00 Quite Low
ischemia 1 50.00 Quite Low
cytokine 9 5.00 Very Low Very Low Very Low
metalloproteinase 6 5.00 Very Low Very Low Very Low
Serotonin 5 5.00 Very Low Very Low Very Low
Inflammation 4 5.00 Very Low Very Low Very Low
Chronic pancreatitis 3 5.00 Very Low Very Low Very Low
fibrosis 2 5.00 Very Low Very Low Very Low
chemokine 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hypoxia 61 98.08 Very High Very High Very High
Pulmonary Hypertension 85 92.84 High High
Cancer 82 92.72 High High
Carcinoma 1 87.44 High High
Increased Venous Pressure Under Development 1 87.28 High High
Metastasis 26 85.28 High High
Lung Cancer 1 83.60 Quite High
Brain Tumor 1 80.72 Quite High
Adhesions 6 70.60 Quite High
Hypertension 2 54.48 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Expression of hypoxia-inducible factor 1 alpha regulated genes was not influenced by cardioplegia and reperfusion, ischemic preconditioning or unstable angina.
Neg (not) Regulation (influenced) of Regulation (regulated) of hypoxia-inducible factor 1 alpha
1) Confidence 0.24 Published 2008 Journal Eur J Cardiothorac Surg Section Body Doc Link 18842422 Disease Relevance 0.06 Pain Relevance 0
stabilization and activation, some evidence indicates that cellular constituents participate in the regulation of HIF-1?
Regulation (participate) of Regulation (regulation) of HIF-1
2) Confidence 0.14 Published 2003 Journal Mol Cancer Section Body Doc Link PMC150383 Disease Relevance 0.64 Pain Relevance 0.04
PHD2 is the key oxygen sensor involved in setting a low steady-state level of HIF-1?
Regulation (involved) of Regulation (setting) of HIF-1
3) Confidence 0.06 Published 2006 Journal Respir Res Section Body Doc Link PMC1351173 Disease Relevance 0.87 Pain Relevance 0

General Comments

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