INT155236

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.53
First Reported 2007
Last Reported 2010
Negated 1
Speculated 1
Reported most in Body
Documents 5
Total Number 6
Disease Relevance 0.66
Pain Relevance 0.46

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (TXN) transport (TXN) mitochondrion (TXN)
small molecule metabolic process (TXN) cell-cell signaling (TXN) cytoplasm (TXN)
Anatomy Link Frequency
ADF 1
TXN (Homo sapiens)
Pain Link Frequency Relevance Heat
diclofenac 80 100.00 Very High Very High Very High
Inflammation 26 81.92 Quite High
alcohol 3 54.36 Quite High
lidocaine 1 52.80 Quite High
cytokine 9 50.00 Quite Low
anticonvulsant 6 50.00 Quite Low
Calcium channel 9 5.00 Very Low Very Low Very Low
cINOD 9 5.00 Very Low Very Low Very Low
Serotonin 8 5.00 Very Low Very Low Very Low
member 8 6 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 57 100.00 Very High Very High Very High
INFLAMMATION 30 81.92 Quite High
Increased Venous Pressure Under Development 1 70.12 Quite High
Lung Cancer 1 61.44 Quite High
Neuroblastoma 10 50.00 Quite Low
Fever 3 47.68 Quite Low
Lymphatic System Cancer 21 31.48 Quite Low
Leukemia 6 30.28 Quite Low
Lifespan 123 5.00 Very Low Very Low Very Low
Sprains And Strains 14 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
When reduced Trx1 was applied in the absence of a regenerating system, a conformational change in CD30 could be observed, but remained incomplete (data not shown).
Negative_regulation (reduced) of Trx1
1) Confidence 0.53 Published 2007 Journal EMBO J Section Body Doc Link PMC1914094 Disease Relevance 0 Pain Relevance 0
These findings indicate that Trx1 reactivity of cell surface receptors is selective and is not determined by the presence of CRDs or the number of ectodomain disulfide bonds.
Neg (not) Spec (determined) Negative_regulation (determined) of Trx1
2) Confidence 0.39 Published 2007 Journal EMBO J Section Body Doc Link PMC1914094 Disease Relevance 0 Pain Relevance 0
Importantly, neither DTT nor TrxR/NADPH had an effect when applied in the absence of Trx1 (Figure 5A, middle panel and data not shown).
Negative_regulation (absence) of Trx1
3) Confidence 0.34 Published 2007 Journal EMBO J Section Body Doc Link PMC1914094 Disease Relevance 0 Pain Relevance 0
By contrast, PPARalpha activation led to the down-regulation of vitamin D(3) up-regulated protein 1 (VDUP-1), the physiological inhibitor of Trx-1.
Negative_regulation (inhibitor) of Trx-1
4) Confidence 0.31 Published 2008 Journal J. Mol. Biol. Section Abstract Doc Link 18848838 Disease Relevance 0.15 Pain Relevance 0.09
M SsTrx, the apoptosis of the diclofenac-treated cells was reduced at all times investigated.

3.5.

Negative_regulation (reduced) of SsTrx associated with apoptosis and diclofenac
5) Confidence 0.13 Published 2010 Journal Journal of Biomedicine and Biotechnology Section Body Doc Link PMC2896885 Disease Relevance 0.51 Pain Relevance 0.34
Laser ablation studies indicate that specific chemosensory amphid neurons are necessary to inhibit dauer formation (ASI, ADF, and ASG), and to promote dauer formation (ASJ) [50],[51].
Negative_regulation (inhibit) of ADF in ADF
6) Confidence 0.00 Published 2008 Journal PLoS Genetics Section Body Doc Link PMC2565500 Disease Relevance 0 Pain Relevance 0.03

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox