INT155249

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Context Info
Confidence 0.50
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.52
Pain Relevance 0.19

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

hydrolase activity, acting on glycosyl bonds (Gla) extracellular region (Gla) Golgi apparatus (Gla)
lysosome (Gla) cytoplasm (Gla)
Anatomy Link Frequency
endothelial cells 2
Gla (Mus musculus)
Pain Link Frequency Relevance Heat
Neuropathic pain 1 76.72 Quite High
Peripheral nervous system 2 64.32 Quite High
Eae 1 53.04 Quite High
hypoalgesia 2 50.80 Quite High
Sciatic nerve 1 36.32 Quite Low
Pain 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Fabry Disease 3 95.52 Very High Very High Very High
Angiokeratoma 1 88.16 High High
Neuropathic Pain 1 76.72 Quite High
Targeted Disruption 2 75.00 Quite High
Congenital Anomalies 1 75.00 Quite High
Hypoalagesia 2 50.80 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Loss of alpha-galactosidase (alpha-Gal) activity leads to the abnormal accumulation of glycosphingolipids in lysosomes predominantly of vascular endothelial cells.
Positive_regulation (leads) of Negative_regulation (Loss) of alpha-galactosidase in endothelial cells
1) Confidence 0.50 Published 2009 Journal Neurobiol. Dis. Section Abstract Doc Link 18848893 Disease Relevance 0.52 Pain Relevance 0.19

General Comments

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