INT155259

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Context Info
Confidence 0.00
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 1.48
Pain Relevance 0.93

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

intracellular (Tnf) extracellular matrix organization (Tnf) DNA binding (RUNX1)
signal transduction (Tnf) extracellular space (Tnf) extracellular region (Tnf)
Anatomy Link Frequency
spinal cord 1
RUNX1 (Homo sapiens)
Tnf (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Etanercept 5 99.92 Very High Very High Very High
intrathecal 1 99.40 Very High Very High Very High
allodynia 2 97.98 Very High Very High Very High
Spinal cord 3 96.76 Very High Very High Very High
Neuropathic pain 2 91.40 High High
Inflammation 1 88.60 High High
Pain 6 85.48 High High
Disease Link Frequency Relevance Heat
Neuropathic Pain 4 97.98 Very High Very High Very High
Injury 1 96.24 Very High Very High Very High
Frailty 10 92.44 High High
INFLAMMATION 1 88.60 High High
Pain 4 85.48 High High
Necrosis 1 84.00 Quite High
Cancer 1 83.64 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Following T13 spinal cord hemisection, we examined the effects on mechanical allodynia and microglial activation of immediate and delayed chronic intrathecal treatment with etanercept, a fusion protein blocker of TNF-alpha.
fusion protein Negative_regulation (blocker) of TNF-alpha in spinal cord associated with allodynia, etanercept, intrathecal and spinal cord
1) Confidence 0.00 Published 2009 Journal Eur J Pain Section Abstract Doc Link 18849175 Disease Relevance 1.48 Pain Relevance 0.93

General Comments

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