INT155290

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Context Info
Confidence 0.03
First Reported 2008
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.00
Pain Relevance 0.48

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (GBE1) generation of precursor metabolites and energy (GBE1) small molecule metabolic process (GBE1)
transferase activity, transferring glycosyl groups (GBE1) carbohydrate metabolic process (GBE1)
GBE1 (Homo sapiens)
Pain Link Frequency Relevance Heat
aspirin 9 99.68 Very High Very High Very High
cINOD 1 91.32 High High
Pain 3 84.24 Quite High
fibrosis 6 5.00 Very Low Very Low Very Low
Central nervous system 5 5.00 Very Low Very Low Very Low
tolerance 2 5.00 Very Low Very Low Very Low
cva 2 5.00 Very Low Very Low Very Low
Neuropathic pain 1 5.00 Very Low Very Low Very Low
ischemia 1 5.00 Very Low Very Low Very Low
Pain score 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 3 96.60 Very High Very High Very High
Apoptosis 1 95.84 Very High Very High Very High
INFLAMMATION 1 91.08 High High
Chronic Renal Failure 20 89.44 High High
Pain 4 84.24 Quite High
Left Ventricular Hypertrophy 3 82.00 Quite High
Fabry Disease 42 73.00 Quite High
Breast Cancer 1 54.00 Quite High
Renal Disease 43 50.00 Quite Low
Disease 26 32.36 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The present work aims at evaluating whether ASA could directly decrease cell glycolysis through inhibition of the major regulatory enzyme within this pathway, 6-phosphofructo-1-kinase (PFK).
Negative_regulation (decrease) of Negative_regulation (inhibition) of enzyme associated with aspirin
1) Confidence 0.03 Published 2009 Journal Biochem. Pharmacol. Section Abstract Doc Link 18851958 Disease Relevance 0.50 Pain Relevance 0.39
Administration of ERT during hemodialysis is not associated with a reduction of the enzyme activity or enzyme loss into the dialysate of agalsidase-alfa (Pastores et al 2007), or agalsidase-beta (Kosch et al 2004).
Negative_regulation (reduction) of Negative_regulation (loss) of enzyme
2) Confidence 0.00 Published 2008 Journal Biologics : Targets & Therapy Section Body Doc Link PMC2727881 Disease Relevance 0.50 Pain Relevance 0.08

General Comments

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