INT155293

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.45
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 1.70
Pain Relevance 0.40

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Casp3) peptidase activity (Casp3) mitochondrion (Casp3)
nucleus (Casp3) intracellular (Casp3) cytoplasm (Casp3)
Anatomy Link Frequency
cleavage 4
Casp3 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 9 93.76 High High
anesthesia 2 89.68 High High
antagonist 1 89.48 High High
cINOD 1 59.92 Quite High
ketamine 1 5.00 Very Low Very Low Very Low
ischemia 1 5.00 Very Low Very Low Very Low
Neurotransmitter 1 5.00 Very Low Very Low Very Low
Kinase C 1 5.00 Very Low Very Low Very Low
isoflurane 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 38 98.32 Very High Very High Very High
Death 2 97.92 Very High Very High Very High
INFLAMMATION 7 93.76 High High
Neurodegenerative Disease 3 75.00 Quite High
Hypoglycemia 1 47.44 Quite Low
Ganglion Cysts 13 5.00 Very Low Very Low Very Low
Telangiectasia 4 5.00 Very Low Very Low Very Low
Pre-eclampsia 3 5.00 Very Low Very Low Very Low
Retinal Diseases 2 5.00 Very Low Very Low Very Low
Edema 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Elevated cleaved caspase-3 was also validated semi-quantitatively by immunoblotting assay.
Positive_regulation (Elevated) of Protein_catabolism (cleaved) of caspase-3
1) Confidence 0.45 Published 2008 Journal Neurosci. Lett. Section Abstract Doc Link 18852026 Disease Relevance 0.38 Pain Relevance 0.09
The proapoptotic effect of rolipram was associated with decreased levels of the prosurvival protein Mcl-1 and increased caspase-3 cleavage.
Positive_regulation (increased) of Protein_catabolism (cleavage) of caspase-3 in cleavage
2) Confidence 0.45 Published 2010 Journal J. Leukoc. Biol. Section Abstract Doc Link 20103769 Disease Relevance 0.76 Pain Relevance 0.31
Analysis of EC samples from Transwell revealed an increase in cleavage of caspase 3, concomitant with a decrease in the anti-apoptotic BCl-xL upon TGF-?
Positive_regulation (increase) of Protein_catabolism (cleavage) of caspase 3 in cleavage associated with apoptosis
3) Confidence 0.12 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2659748 Disease Relevance 0.56 Pain Relevance 0

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox