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Context Info
Confidence 0.35
First Reported 2009
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.74
Pain Relevance 0.43

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (EFNB1) cell adhesion (EFNB1) nucleus (EFNB1)
cell-cell signaling (EFNB1) cytoplasm (EFNB1)
Anatomy Link Frequency
urethra 1
EFNB1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Spinal cord 1 96.40 Very High Very High Very High
cINOD 1 96.00 Very High Very High Very High
intrathecal 1 93.00 High High
referred pain 1 91.84 High High
Inflammation 1 87.96 High High
Dorsal horn 1 80.88 Quite High
Pain 1 62.48 Quite High
Disease Link Frequency Relevance Heat
INFLAMMATION 2 95.76 Very High Very High Very High
Referred Pain 1 91.84 High High
Stress Incontinence 5 90.24 High High
Low Back Pain 1 62.48 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
All these results suggest that EphBR-ephrinB interactions, which provoke Src-family kinase-dependent NMDAR NR2B phosphorylation at the lumbosacral spinal cord level, are involved in cross-organ sensitization, contributing to the development of viscero-visceral referred pain between the bowel and the urethra.
ephrinB Binding (interactions) of in urethra associated with stress incontinence, referred pain and spinal cord
1) Confidence 0.35 Published 2010 Journal Am. J. Physiol. Renal Physiol. Section Abstract Doc Link 19864302 Disease Relevance 0.56 Pain Relevance 0.29
The molecular mechanism of bee venom phospholipase A(2) inactivation has been identified, and the ligand-enzyme complex formation is guided by either non-covalent and covalent interactions.
ligand-enzyme Binding (formation) of
2) Confidence 0.15 Published 2009 Journal Bioorg. Chem. Section Abstract Doc Link 18945473 Disease Relevance 0.18 Pain Relevance 0.14

General Comments

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