INT155532

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Context Info
Confidence 0.26
First Reported 2008
Last Reported 2010
Negated 1
Speculated 1
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 0.32
Pain Relevance 0.22

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (IL1B) signal transduction (IL1B) extracellular space (IL1B)
aging (IL1B) extracellular region (IL1B) cell-cell signaling (IL1B)
IL1B (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 35 94.64 High High
addiction 5 90.28 High High
Osteoarthritis 41 70.96 Quite High
rheumatoid arthritis 2 70.40 Quite High
antagonist 11 64.56 Quite High
COX-2 inhibitor 2 53.84 Quite High
Pain 16 50.00 Quite Low
cytokine 10 50.00 Quite Low
spinal inflammation 2 50.00 Quite Low
agonist 22 25.84 Quite Low
Disease Link Frequency Relevance Heat
INFLAMMATION 44 94.64 High High
Injury 6 87.00 High High
Osteoarthritis 41 70.96 Quite High
Rheumatoid Arthritis 2 70.40 Quite High
Pain 17 50.00 Quite Low
Low Back Pain 2 50.00 Quite Low
Apoptosis 19 5.00 Very Low Very Low Very Low
Disease 15 5.00 Very Low Very Low Very Low
Arthritis 4 5.00 Very Low Very Low Very Low
Death 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
RESULTS: Surgery induced no significant changes in systemic values of TNFalpha and IL-1beta.
Neg (no) Regulation (changes) of Regulation (values) of IL-1beta
1) Confidence 0.26 Published 2009 Journal Scand. J. Clin. Lab. Invest. Section Body Doc Link 18946778 Disease Relevance 0.09 Pain Relevance 0
We therefore compared the mechanisms regulating IL-1?
Regulation (mechanisms) of Regulation (regulating) of IL-1
2) Confidence 0.08 Published 2010 Journal The Journal of Biological Chemistry Section Body Doc Link PMC2906308 Disease Relevance 0 Pain Relevance 0.08
These results clearly demonstrate the difficulty in teasing out the specific roles played by both NO and ROS in order to determine their involvement in IL-1-induced NF-?
Spec (determine) Regulation (determine) of Spec (determine) Regulation (involvement) of IL-1
3) Confidence 0.04 Published 2008 Journal Arthritis Res Ther Section Body Doc Link PMC2582805 Disease Relevance 0.24 Pain Relevance 0.14

General Comments

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