INT155564

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Context Info
Confidence 0.43
First Reported 2007
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 0.53
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (Efemp2) proteinaceous extracellular matrix (Efemp2)
Efemp2 (Mus musculus)
Pain Link Frequency Relevance Heat
Hippocampus 2 50.20 Quite High
interstitial cystitis 2 50.00 Quite Low
ketamine 4 5.00 Very Low Very Low Very Low
anesthesia 4 5.00 Very Low Very Low Very Low
cva 4 5.00 Very Low Very Low Very Low
cytokine 2 5.00 Very Low Very Low Very Low
Central nervous system 2 5.00 Very Low Very Low Very Low
amygdala 2 5.00 Very Low Very Low Very Low
spastic colon 1 5.00 Very Low Very Low Very Low
depression 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Congenital Anomalies 13 75.00 Quite High
Targeted Disruption 33 73.52 Quite High
Sprains And Strains 8 71.60 Quite High
Intellectual Impairment 4 71.52 Quite High
Syndrome 2 69.24 Quite High
Marfan Syndrome 2 52.96 Quite High
Mixed Connective Tissue Disorder 2 51.44 Quite High
Disease 25 50.00 Quite Low
Myotonic Dystrophy 22 50.00 Quite Low
Interstitial Cystitis 2 50.00 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In the present study, arterial pathologies in fibulin-4+/?
Negative_regulation (pathologies) of fibulin-4
1) Confidence 0.43 Published 2007 Journal PLoS ONE Section Body Doc Link PMC1794134 Disease Relevance 0.39 Pain Relevance 0.03
If so, perhaps housing the fibulin-4+/?
Negative_regulation (housing) of fibulin-4
2) Confidence 0.43 Published 2007 Journal PLoS ONE Section Body Doc Link PMC1794134 Disease Relevance 0.15 Pain Relevance 0
PI3, SERPINB4, CYP2C8, EFEMP2 and SEPP1 were decreased, and AKR1C2 and MKNK1 were increased in interstitial cystitis cases.
Negative_regulation (decreased) of EFEMP2
3) Confidence 0.08 Published 2008 Journal J. Urol. Section Body Doc Link 18951569 Disease Relevance 0 Pain Relevance 0
If this is the case, then the accumulation of CCUG repeats in large aggregates might lead to the reduction of decay of the mutant intron 1 of ZNF9 in DM2 cells.
Negative_regulation (reduction) of mutant intron 1
4) Confidence 0.01 Published 2010 Journal Current Genomics Section Body Doc Link PMC2874224 Disease Relevance 0 Pain Relevance 0

General Comments

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