INT155583

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Context Info
Confidence 0.37
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.42
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Mtor) mitochondrion (Mtor) Golgi apparatus (Mtor)
endoplasmic reticulum (Mtor) nucleus (Mtor) kinase activity (Mtor)
Mtor (Mus musculus)
Pain Link Frequency Relevance Heat
Chronic pancreatitis 4 50.00 Quite Low
Pain 3 50.00 Quite Low
Analgesic 1 10.00 Low Low
fibrosis 10 5.00 Very Low Very Low Very Low
anesthesia 3 5.00 Very Low Very Low Very Low
ketamine 2 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Coronary Heart Disease 13 95.56 Very High Very High Very High
Hypertrophy 9 86.60 High High
Tuberous Sclerosis 1 76.00 Quite High
Pancreatitis 4 54.84 Quite High
Stress 10 53.08 Quite High
Pain 2 52.08 Quite High
Left Ventricular Hypertrophy 10 50.00 Quite Low
Fibrosis 10 5.00 Very Low Very Low Very Low
Myocardial Infarction 3 5.00 Very Low Very Low Very Low
Heart Disease 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The reduction in the level of TBARS and increase in FRAP were significantly higher in the antioxidant group compared with the placebo group (TBARS: placebo 1.2+/-2.7 vs antioxidant 3.5+/-3.4 nmol/mL; P= .001; 95% CI 0.96, 3.55; FRAP: placebo -5.6+/-154.9 vs antioxidant 97.8+/-134.9 microMFe(+2) liberated, P= .001, 95% CI 44.98, 161.7).
Negative_regulation (reduction) of Positive_regulation (increase) of FRAP
1) Confidence 0.37 Published 2009 Journal Gastroenterology Section Body Doc Link 18952082 Disease Relevance 0.16 Pain Relevance 0
Therefore we next examined whether the anti-hypertrophic effect of MEF2C depletion is related to a defective activation of mTOR (mammalian Target of Rapamycin).
Negative_regulation (defective) of Positive_regulation (activation) of mTOR
2) Confidence 0.05 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2794538 Disease Relevance 0.26 Pain Relevance 0

General Comments

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