INT15577

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Context Info
Confidence 0.14
First Reported 1991
Last Reported 1991
Negated 0
Speculated 2
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0
Pain Relevance 0.88

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signal transduction (GNRH1) extracellular space (GNRH1) extracellular region (GNRH1)
cell-cell signaling (GNRH1)
Lhb (Mus musculus)
GNRH1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Endogenous opioid 2 98.54 Very High Very High Very High
narcan 20 97.60 Very High Very High Very High
opiate 2 97.08 Very High Very High Very High
antagonist 2 96.80 Very High Very High Very High
ketamine 2 85.44 High High
Opioid 6 25.00 Low Low

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We have systematically investigated the involvement of endogenous opioids in gonadotropin secretion during primate sexual maturation by examining LH/FSH responses to gonadotropin-releasing hormone (GnRH) and changes in LH secretion during infusions of saline or naloxone, an opiate antagonist, in ten male chimpanzees between one and nine years of age.
LH Spec (examining) Positive_regulation (responses) of gonadotropin-releasing hormone associated with antagonist, narcan, endogenous opioid and opiate
1) Confidence 0.14 Published 1991 Journal Brain Res. Bull. Section Abstract Doc Link 1742612 Disease Relevance 0 Pain Relevance 0.44
We have systematically investigated the involvement of endogenous opioids in gonadotropin secretion during primate sexual maturation by examining LH/FSH responses to gonadotropin-releasing hormone (GnRH) and changes in LH secretion during infusions of saline or naloxone, an opiate antagonist, in ten male chimpanzees between one and nine years of age.
LH Spec (examining) Positive_regulation (responses) of GnRH associated with antagonist, narcan, endogenous opioid and opiate
2) Confidence 0.14 Published 1991 Journal Brain Res. Bull. Section Abstract Doc Link 1742612 Disease Relevance 0 Pain Relevance 0.44

General Comments

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