INT15578

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.07
First Reported 1991
Last Reported 1999
Negated 1
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 0
Pain Relevance 1.22

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (GNRH1) extracellular space (GNRH1) extracellular region (GNRH1)
cell-cell signaling (GNRH1)
Anatomy Link Frequency
pituitary gland 2
GNRH1 (Homo sapiens)
Lhb (Mus musculus)
Pain Link Frequency Relevance Heat
Serotonin 8 100.00 Very High Very High Very High
narcan 20 98.76 Very High Very High Very High
opiate 2 98.24 Very High Very High Very High
Endogenous opioid 2 98.14 Very High Very High Very High
antagonist 3 97.96 Very High Very High Very High
halothane 2 94.52 High High
ketamine 2 87.76 High High
Opioid 6 25.00 Low Low
anesthesia 1 25.00 Low Low

|}

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We have systematically investigated the involvement of endogenous opioids in gonadotropin secretion during primate sexual maturation by examining LH/FSH responses to gonadotropin-releasing hormone (GnRH) and changes in LH secretion during infusions of saline or naloxone, an opiate antagonist, in ten male chimpanzees between one and nine years of age.
gonadotropin-releasing hormone Regulation (changes) of Localization (secretion) of LH associated with antagonist, narcan, endogenous opioid and opiate
1) Confidence 0.07 Published 1991 Journal Brain Res. Bull. Section Abstract Doc Link 1742612 Disease Relevance 0 Pain Relevance 0.45
We have systematically investigated the involvement of endogenous opioids in gonadotropin secretion during primate sexual maturation by examining LH/FSH responses to gonadotropin-releasing hormone (GnRH) and changes in LH secretion during infusions of saline or naloxone, an opiate antagonist, in ten male chimpanzees between one and nine years of age.
GnRH Regulation (changes) of Localization (secretion) of LH associated with antagonist, narcan, endogenous opioid and opiate
2) Confidence 0.07 Published 1991 Journal Brain Res. Bull. Section Abstract Doc Link 1742612 Disease Relevance 0 Pain Relevance 0.45
In comparison with the vehicle-treated controls, the response of plasma LH to exogenous GnRH was not altered by serotonin or cyproheptadine in either season, which shows that serotonin has no effect on LH release at the pituitary gland level in these animals.
GnRH Neg (no) Regulation (effect) of Localization (release) of LH in pituitary gland associated with serotonin
3) Confidence 0.05 Published 1999 Journal Reprod. Fertil. Dev. Section Abstract Doc Link 10735553 Disease Relevance 0 Pain Relevance 0.33

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox