INT155803

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Context Info
Confidence 0.71
First Reported 2009
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 5
Disease Relevance 3.09
Pain Relevance 0.85

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (Dtnbp1) endoplasmic reticulum (Dtnbp1) plasma membrane (Dtnbp1)
nucleus (Dtnbp1) cytoplasm (Dtnbp1)
Anatomy Link Frequency
cortex 3
cerebral cortex 1
hippocampus 1
Dtnbp1 (Mus musculus)
Pain Link Frequency Relevance Heat
cerebral cortex 3 99.84 Very High Very High Very High
Hippocampus 2 97.76 Very High Very High Very High
agonist 3 93.52 High High
Glutamate receptor 3 93.20 High High
Dopamine 26 91.56 High High
Glutamate 9 88.64 High High
Eae 4 68.88 Quite High
nMDA receptor 3 47.92 Quite Low
withdrawal 2 25.00 Low Low
hypoalgesia 2 25.00 Low Low
Disease Link Frequency Relevance Heat
Schizophrenia 123 99.92 Very High Very High Very High
Cognitive Disorder 9 41.84 Quite Low
Psychosis 21 36.32 Quite Low
Manic Depressive Disorder 9 31.44 Quite Low
Anxiety Disorder 29 25.00 Low Low
Nociception 2 25.00 Low Low
Hypoalagesia 2 25.00 Low Low
Post-traumatic Stress Disorder 54 5.00 Very Low Very Low Very Low
Opiate Addiction 39 5.00 Very Low Very Low Very Low
Nicotine Addiction 33 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Reduced DTNBP1 mRNA expression in cerebral cortex has been associated with risk haplotypes for schizophrenia [10].
Transcription (expression) of DTNBP1 in cerebral cortex associated with cerebral cortex and schizophrenia
1) Confidence 0.71 Published 2010 Journal Behav Brain Funct Section Body Doc Link PMC2911395 Disease Relevance 0.83 Pain Relevance 0.23
Reduced DTNBP1 mRNA and protein expression has been found in the hippocampal formation and dorsolateral prefrontal cortex of schizophrenia patients [11-13].
Transcription (expression) of DTNBP1 in cortex associated with schizophrenia
2) Confidence 0.71 Published 2010 Journal Behav Brain Funct Section Body Doc Link PMC2911395 Disease Relevance 0.84 Pain Relevance 0.22
Reduced DTNBP1 mRNA and protein expression has been found in the hippocampal formation and dorsolateral prefrontal cortex of schizophrenia patients [11-13].
Transcription (expression) of DTNBP1 in cortex associated with schizophrenia
3) Confidence 0.68 Published 2010 Journal Behav Brain Funct Section Body Doc Link PMC2911395 Disease Relevance 0.84 Pain Relevance 0.22
Dysbindin-1 mRNA and protein levels are significantly reduced in the prefrontal cortex and hippocampus of schizophrenia subjects.
Transcription (levels) of Dysbindin-1 in hippocampus associated with hippocampus and schizophrenia
4) Confidence 0.53 Published 2009 Journal Behav. Brain Res. Section Abstract Doc Link 18984010 Disease Relevance 0.28 Pain Relevance 0.08
Dysbindin-1 mRNA and protein levels are significantly reduced in the prefrontal cortex and hippocampus of schizophrenia subjects.
Transcription (levels) of Dysbindin-1 in cortex associated with hippocampus and schizophrenia
5) Confidence 0.18 Published 2009 Journal Behav. Brain Res. Section Abstract Doc Link 18984010 Disease Relevance 0.28 Pain Relevance 0.08

General Comments

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