INT155861

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Context Info
Confidence 0.42
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 3.29
Pain Relevance 0.63

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

isomerase activity (ENOSF1) mitochondrion (ENOSF1) molecular_function (ENOSF1)
cellular_component (ENOSF1) biological_process (ENOSF1)
ENOSF1 (Homo sapiens)
Pain Link Frequency Relevance Heat
qutenza 9 98.48 Very High Very High Very High
Inflammation 5 85.56 High High
Pain 2 5.00 Very Low Very Low Very Low
Analgesic 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Syndrome 38 100.00 Very High Very High Very High
Infection 16 99.76 Very High Very High Very High
Apoptosis 8 98.84 Very High Very High Very High
Injury 37 97.64 Very High Very High Very High
Immunodeficiency 9 93.92 High High
Agammaglobulinemia 2 89.76 High High
Stress 4 85.88 High High
Granulomatous Inflammation 4 85.56 High High
Herpes Simplex Encephalitis 1 85.28 High High
Lymphopenia 1 79.08 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The knowledge of a decrease in T-RTS may promote a more aggressive approach to patients in the trauma bay.


Negative_regulation (decrease) of RTS associated with injury
1) Confidence 0.42 Published 2008 Journal Int J Emerg Med Section Body Doc Link PMC2536180 Disease Relevance 0.40 Pain Relevance 0
The distinct effect of capsaicin-induced apoptosis on the expression pattern of HepG2 proteins includes the downregulation of some antioxidant enzymes including aldose reductase (AR), catalase, enolase 1, peroxiredoxin 1, but upregulation of peroxiredoxin 6, cytochrome c oxidase, and SOD2.
Negative_regulation (downregulation) of enolase 1 associated with qutenza and apoptosis
2) Confidence 0.11 Published 2008 Journal Proteomics Section Abstract Doc Link 18991268 Disease Relevance 0.79 Pain Relevance 0.58
Recently, an increasing number of reports on increased susceptibility to infections and immune deficiency in RTS are emerging.
Negative_regulation (deficiency) of RTS associated with syndrome and infection
3) Confidence 0.04 Published 2010 Journal Orphanet J Rare Dis Section Body Doc Link PMC3009952 Disease Relevance 2.10 Pain Relevance 0.04

General Comments

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