INT15594

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Context Info
Confidence 0.26
First Reported 1991
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 0.96
Pain Relevance 1.14

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Ldha) mitochondrion (Ldha) oxidoreductase activity (Ldha)
carbohydrate metabolic process (Ldha) cytoplasm (Ldha)
Anatomy Link Frequency
plasma 1
lung 1
Ldha (Mus musculus)
Pain Link Frequency Relevance Heat
cocaine 12 99.02 Very High Very High Very High
Buprenorphine 7 98.80 Very High Very High Very High
narcan 3 89.56 High High
Inflammation 9 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
abdominal pain 1 5.00 Very Low Very Low Very Low
isoflurane 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Weight Loss 11 96.60 Very High Very High Very High
Jaundice 1 94.68 High High
Pain 1 92.36 High High
Immunization 2 90.84 High High
Infection 40 85.04 High High
Toxicity 4 80.72 Quite High
Shock 5 73.12 Quite High
Acute Liver Failure 1 50.00 Quite Low
Influenza Virus Infection 30 47.00 Quite Low
Respiratory Syncytial Virus 3 38.80 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
When tested 0.5, 1, 2, 4, 8 and 24 hrs after cocaine administration, sublethal dose of cocaine (80 mg/kg ip) injection resulted in significant increase in the plasma lactate dehydrogenase (LDH) levels.
Positive_regulation (increase) of plasma lactate dehydrogenase in plasma associated with cocaine
1) Confidence 0.26 Published 1991 Journal Life Sci. Section Abstract Doc Link 1745104 Disease Relevance 0.30 Pain Relevance 1.14
The lack of any lung damage associated with the PCN treatment was further supported by the absence of any increase in the levels of serum albumin (Figure 3C) and lactate dehydrogenase (Figure 3D) recovered in the BALF of these mice at this time and the absence of any weight loss during the PCN treatment regimen (data not shown).
Positive_regulation (increase) of lactate dehydrogenase in lung associated with weight loss
2) Confidence 0.14 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2743193 Disease Relevance 0.48 Pain Relevance 0
INVESTIGATIONS: The activities of SGOT (756 U/I), SGPT (1450 U/I). gamma GT (164 U/I) and lactate dehydrogenase (539 U/I) as well as total bilirubin level (7.5 mg/dl) were elevated.
Positive_regulation (elevated) of lactate dehydrogenase
3) Confidence 0.05 Published 1997 Journal Dtsch. Med. Wochenschr. Section Body Doc Link 9213536 Disease Relevance 0.19 Pain Relevance 0

General Comments

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