INT155958

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Context Info
Confidence 0.15
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0.64
Pain Relevance 0.48

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Kcnk2) plasma membrane (Akap5) protein complex (Akap5)
cytoplasm (Akap5)
Kcnk2 (Mus musculus)
Akap5 (Mus musculus)
Pain Link Frequency Relevance Heat
Pain 2 92.48 High High
depression 2 91.24 High High
ischemia 2 88.40 High High
potassium channel 4 81.32 Quite High
Disease Link Frequency Relevance Heat
Pain 2 92.48 High High
Depression 2 91.24 High High
Brain Hemorrhage 2 88.40 High High
Targeted Disruption 2 84.72 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Furthermore, the association of AKAP150 with TREK1 channels integrates them into postsynaptic scaffolds where G protein-coupled membrane receptors and channels dock simultaneously.
TREK1 Binding (association) of AKAP150
1) Confidence 0.15 Published 2008 Journal Methods Mol. Biol. Section Abstract Doc Link 18998088 Disease Relevance 0.28 Pain Relevance 0.21
Among the identified partners, the A-Kinase Anchoring Protein AKAP150 binds to a regulatory domain of TREK1 and acts as a molecular switch.
TREK1 Binding (binds) of AKAP150
2) Confidence 0.15 Published 2008 Journal Methods Mol. Biol. Section Abstract Doc Link 18998088 Disease Relevance 0.36 Pain Relevance 0.26

General Comments

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