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Context Info
Confidence 0.10
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.53
Pain Relevance 0.95

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Nfkb1, Cyp11a1) DNA binding (Nfkb1) protein complex (Nfkb1)
lipid metabolic process (Cyp11a1) cytoplasm (Nfkb1) cytosol (Nfkb1)
Anatomy Link Frequency
liver 2
Nfkb1 (Mus musculus)
Cyp11a1 (Mus musculus)
Pain Link Frequency Relevance Heat
Paracetamol 16 99.24 Very High Very High Very High
cva 1 89.68 High High
antagonist 2 75.00 Quite High
Disease Link Frequency Relevance Heat
Injury 5 98.48 Very High Very High Very High
Hemorrhage 1 89.68 High High
Necrosis 1 89.16 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Collectively, NF-kappaB was activated without any stimuli by the genetic disruption of IL-1ra, and suppressed cytochrome P450 enzyme expression, thereby reducing APAP-induced liver injury.
NF-kappaB Negative_regulation (suppressed) of Gene_expression (expression) of cytochrome P450 enzyme in liver associated with paracetamol and injury
1) Confidence 0.10 Published 2009 Journal Lab. Invest. Section Abstract Doc Link 19002106 Disease Relevance 0.53 Pain Relevance 0.95

General Comments

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