INT156008

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Context Info
Confidence 0.17
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 1.92
Pain Relevance 1.47

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Bcl2, Aifm1) cytoplasm (Bcl2, Aifm1) cytosol (Bcl2, Aifm1)
nucleus (Bcl2, Aifm1) cell morphogenesis (Bcl2) endoplasmic reticulum (Bcl2)
Anatomy Link Frequency
BxPC-3 3
AsPC-1 1
Bcl2 (Mus musculus)
Aifm1 (Mus musculus)
Pain Link Frequency Relevance Heat
qutenza 24 98.80 Very High Very High Very High
Disease Link Frequency Relevance Heat
Apoptosis 10 86.24 High High
Pancreatic Cancer 14 80.48 Quite High
Death 2 75.00 Quite High
Cancer 4 70.52 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Exposure of AsPC-1 and BxPC-3 cells to capsaicin was also associated with increased expression of Bax, down-regulation of bcl-2, survivin and significant release of cytochrome c and AIF in the cytosol.
bcl-2 Regulation (regulation) of Localization (release) of AIF in BxPC-3 associated with qutenza
1) Confidence 0.17 Published 2008 Journal Apoptosis Section Abstract Doc Link 19002586 Disease Relevance 0.96 Pain Relevance 0.73
Exposure of AsPC-1 and BxPC-3 cells to capsaicin was also associated with increased expression of Bax, down-regulation of bcl-2, survivin and significant release of cytochrome c and AIF in the cytosol.
bcl-2 Regulation (regulation) of in AsPC-1 Localization (release) of AIF in BxPC-3 associated with qutenza
2) Confidence 0.06 Published 2008 Journal Apoptosis Section Abstract Doc Link 19002586 Disease Relevance 0.96 Pain Relevance 0.73

General Comments

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