INT15605

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Context Info
Confidence 0.40
First Reported 1983
Last Reported 1991
Negated 0
Speculated 0
Reported most in Title
Documents 4
Total Number 4
Disease Relevance 0
Pain Relevance 1.36

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (GNRHR) signal transducer activity (GNRHR)
Anatomy Link Frequency
hypothalamus 2
GNRHR (Homo sapiens)
Pain Link Frequency Relevance Heat
Endogenous opioid 4 99.98 Very High Very High Very High
narcan 7 99.64 Very High Very High Very High
opiate 6 95.56 Very High Very High Very High
agonist 2 94.92 High High
antagonist 3 90.08 High High
Opioid 3 75.00 Quite High
Morphine 2 59.68 Quite High
Enkephalin 1 58.84 Quite High
opioid receptor 1 53.20 Quite High

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Endogenous opioid regulation of gonadotropin-releasing hormone release from the human fetal hypothalamus in vitro.
Regulation (regulation) of Localization (release) of gonadotropin-releasing hormone in hypothalamus associated with endogenous opioid
1) Confidence 0.40 Published 1983 Journal J. Clin. Endocrinol. Metab. Section Title Doc Link 6311863 Disease Relevance 0 Pain Relevance 0.59
Steroid hormones modulate the release of immunoreactive gonadotropin-releasing hormone from cultured human placental cells.
Regulation (modulate) of Localization (release) of gonadotropin-releasing hormone
2) Confidence 0.21 Published 1990 Journal J. Clin. Endocrinol. Metab. Section Title Doc Link 2156890 Disease Relevance 0 Pain Relevance 0.43
Substantial evidence now exists to indicate that the endogenous hypothalamic opioidergic mechanism(s) represents one of the important controlling systems for release of gonadotropin-releasing hormone.
Regulation (controlling) of Localization (release) of gonadotropin-releasing hormone
3) Confidence 0.18 Published 1985 Journal Am. J. Obstet. Gynecol. Section Abstract Doc Link 2990210 Disease Relevance 0 Pain Relevance 0.35
Gonadotropin-releasing hormone pulses: regulators of gonadotropin synthesis and ovulatory cycles.
Regulation (regulators) of Localization (releasing) of Gonadotropin-releasing hormone
4) Confidence 0.11 Published 1991 Journal Recent Prog. Horm. Res. Section Title Doc Link 1745819 Disease Relevance 0 Pain Relevance 0

General Comments

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