INT156376

Context Info Confidence 0.56 First Reported 2009 Last Reported 2009 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 1 Disease Relevance 0.16 Pain Relevance 0.65

plasma membrane (Dlg4) protein complex assembly (Dlg4) response to stress (Dlg4) cytoplasm (Dlg4)

Dlg4 (Rattus norvegicus)

Pain Link Frequency Relevance Heat Morphine 9 99.42 nMDA receptor 1 75.00 Opioid 1 46.80 Neurobehavioral 1 45.52

Disease Link Frequency Relevance Heat Cognitive Disorder 3 84.44

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

The real-time polymerase chain reaction results showed that prenatal morphine exposure caused significant decreases in mRNA levels of the PSD-95 and three NMDAR subunits (NR1, NR2A, and NR2B) in offspring (P14 and P45).

Negative_regulation (decreases) of Transcription (levels) of PSD-95 associated with morphine

1) Confidence 0.56 Published 2009 Journal Neuroscience Section Abstract Doc Link 19041927 Disease Relevance 0.16 Pain Relevance 0.65

General Comments

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