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Context Info
Confidence 0.43
First Reported 2009
Last Reported 2009
Negated 0
Speculated 1
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.17
Pain Relevance 0.51

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plasma membrane (Dlg4) protein complex assembly (Dlg4) response to stress (Dlg4)
cytoplasm (Dlg4)
Dlg4 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Morphine 9 99.80 Very High Very High Very High
nMDA receptor 1 75.00 Quite High
Neurobehavioral 1 25.00 Low Low
Opioid 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Cognitive Disorder 3 90.12 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In this study, we determined whether prenatal morphine exposure altered the synaptic complex association between PSD-95 and three major NMDAR subunits (NR1, NR2A, and NR2B), at the mRNA and protein levels, within the hippocampal CA1 subregion (an important integration area for mammalian learning and memory) of rat offspring along with the performance of long-term cognitive functions.
Spec (whether) Regulation (altered) of PSD-95 Binding (association) of associated with cognitive disorder and morphine
1) Confidence 0.43 Published 2009 Journal Neuroscience Section Abstract Doc Link 19041927 Disease Relevance 0.17 Pain Relevance 0.51

General Comments

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