INT156396

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Context Info
Confidence 0.55
First Reported 2005
Last Reported 2011
Negated 0
Speculated 0
Reported most in Body
Documents 61
Total Number 61
Disease Relevance 13.63
Pain Relevance 8.17

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
neuronal 7
neurons 5
spinal cord 2
IB4 2
eye 2
Tg(CAG-EGFP)D4Nagy (Mus musculus)
Pain Link Frequency Relevance Heat
Spinal cord 503 100.00 Very High Very High Very High
nMDA receptor 158 100.00 Very High Very High Very High
superficial lamina 12 100.00 Very High Very High Very High
nociceptor 69 99.96 Very High Very High Very High
gABA 47 99.84 Very High Very High Very High
Calcitonin gene-related peptide 123 98.80 Very High Very High Very High
substance P 54 98.68 Very High Very High Very High
intrathecal 166 97.52 Very High Very High Very High
Glutamate 28 97.24 Very High Very High Very High
Sciatic nerve 116 96.68 Very High Very High Very High
Disease Link Frequency Relevance Heat
Cancer 410 100.00 Very High Very High Very High
Necrosis 50 99.96 Very High Very High Very High
Targeted Disruption 375 99.72 Very High Very High Very High
Sprains And Strains 321 99.68 Very High Very High Very High
Injury 270 99.68 Very High Very High Very High
Demyelinating Disease 690 99.36 Very High Very High Very High
Hepatitis 38 99.36 Very High Very High Very High
Nociception 128 98.40 Very High Very High Very High
Death 49 98.00 Very High Very High Very High
Nervous System Injury 72 97.84 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Furthermore, in the matrix compartment of the neostriatum of the three lines, intense GFP immunoreactivity was densely distributed in the neuronal cell bodies and neuropil, and matrix neurons displayed > 94% co-localization for GFP and PPE immunoreactivities.
Localization (localization) of GFP in neuronal
1) Confidence 0.55 Published 2008 Journal Eur. J. Neurosci. Section Abstract Doc Link 19046386 Disease Relevance 0.24 Pain Relevance 0.26
+ gate were analyzed for staining with NK1.1 or CD1d tetramer and GFP.


Localization (tetramer) of GFP
2) Confidence 0.36 Published 2005 Journal PLoS Biology Section Body Doc Link PMC1073691 Disease Relevance 0.25 Pain Relevance 0
reporter to proteasomal inhibition, as well as to monitor the kinetics of GFP?
Localization (kinetics) of GFP
3) Confidence 0.34 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2690827 Disease Relevance 0.18 Pain Relevance 0.07
is coincident with increased ubiquitination following proteasomal inhibition (Figure 2C), confirming the physiological relevance of GFP?.
Localization (relevance) of GFP
4) Confidence 0.34 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2690827 Disease Relevance 0.12 Pain Relevance 0
Primary neuronal cultures from GFP?
Localization (cultures) of GFP in neuronal
5) Confidence 0.34 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2690827 Disease Relevance 0.19 Pain Relevance 0.08
To this end, we have engineered a transgenic mouse expressing a reporter (GFP?)
Localization (reporter) of GFP associated with targeted disruption
6) Confidence 0.34 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2690827 Disease Relevance 0.60 Pain Relevance 0
In fact, the GFP-expressing tumor was sufficiently bright to enable its instant localization (Fig. 5).
Localization (localization) of GFP associated with cancer
7) Confidence 0.32 Published 2010 Journal Surg Endosc Section Body Doc Link PMC3003784 Disease Relevance 0.58 Pain Relevance 0
To meet our objective of dual functionality through live video, the exposure time was set at 110 ms, and the gain was set to 97.Fig. 1Fluorescence laparoscope for visualization and localization of green fluorescent protein (GFP)-labeled tumors in mice.
Localization (localization) of GFP associated with cancer
8) Confidence 0.31 Published 2010 Journal Surg Endosc Section Body Doc Link PMC3003784 Disease Relevance 0.15 Pain Relevance 0.03
RFP+ and RFP/GFP double-positive perivascular cells were often in close proximity (Figure 5D) and co-localized in the perivascular zone.
Localization (localized) of GFP
9) Confidence 0.25 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2965160 Disease Relevance 0.33 Pain Relevance 0.04
Figure 6A shows a periventricular lesion visualized for CCR2 (RFP, red), CX3CR1 (GFP, green), and 7/4 (Cy5, blue).
Localization (visualized) of GFP
10) Confidence 0.25 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2965160 Disease Relevance 0.25 Pain Relevance 0.17
The colocalization of eGFP and CtBP2 strongly suggest that the OPL layer was transduced (Figure 2F,H).
Localization (colocalization) of eGFP
11) Confidence 0.24 Published 2009 Journal Molecular Vision Section Body Doc Link PMC2713732 Disease Relevance 0.72 Pain Relevance 0
Further evidence suggesting GFP localization in the central processes of primary afferent neurons was the observation of labeling in dorsal roots as well as in the dorsal columns.
Localization (localization) of GFP in dorsal
12) Confidence 0.23 Published 2010 Journal Mol Pain Section Body Doc Link PMC2900238 Disease Relevance 0 Pain Relevance 0.41
Colocalization of EGFP Positive Cells with Viral Antigen
Localization (Colocalization) of EGFP
13) Confidence 0.22 Published 2010 Journal Interdisciplinary Perspectives on Infectious Diseases Section Body Doc Link PMC2905936 Disease Relevance 0.77 Pain Relevance 0.03
There is a high degree of colocalization of EGFP and viral antigen in the majority of sections analyzed.
Localization (colocalization) of EGFP
14) Confidence 0.22 Published 2010 Journal Interdisciplinary Perspectives on Infectious Diseases Section Body Doc Link PMC2905936 Disease Relevance 0.85 Pain Relevance 0.10
In mouse DRG, GFP was seen in neuronal cell bodies and fibers after both rAAV5-GFP (as shown in Fig 1C) and rAAV8-GFP treatment (data not shown).
Localization (seen) of GFP in neuronal
15) Confidence 0.21 Published 2010 Journal Mol Pain Section Body Doc Link PMC2900238 Disease Relevance 0 Pain Relevance 0.37
In mouse DRG, GFP was seen in neuronal cell bodies and fibers after both rAAV5-GFP (as shown in Fig 1C) and rAAV8-GFP treatment (data not shown).
Localization (treatment) of rAAV8-GFP in neuronal
16) Confidence 0.21 Published 2010 Journal Mol Pain Section Body Doc Link PMC2900238 Disease Relevance 0 Pain Relevance 0.40
We further tested NR2 subunit composition of synaptic NMDA receptors for both EGFP+ and EGFP- neurons using a pharmacological approach.
Localization (receptors) of EGFP in neurons associated with nmda receptor
17) Confidence 0.21 Published 2010 Journal Mol Pain Section Body Doc Link PMC2879240 Disease Relevance 0 Pain Relevance 0.28
We further tested NR2 subunit composition of synaptic NMDA receptors for both EGFP+ and EGFP- neurons using a pharmacological approach.
Localization (receptors) of EGFP in neurons associated with nmda receptor
18) Confidence 0.21 Published 2010 Journal Mol Pain Section Body Doc Link PMC2879240 Disease Relevance 0 Pain Relevance 0.28
In contrast, in RSMHV2EGFP-infected mice EGFP completely colocalized with GFAP (Figure 19).
Localization (colocalized) of EGFP
19) Confidence 0.21 Published 2010 Journal Interdisciplinary Perspectives on Infectious Diseases Section Body Doc Link PMC2905936 Disease Relevance 0.60 Pain Relevance 0.10
In mouse DRG, GFP was seen in neuronal cell bodies and fibers after both rAAV5-GFP (as shown in Fig 1C) and rAAV8-GFP treatment (data not shown).
Localization (seen) of GFP in neuronal
20) Confidence 0.18 Published 2010 Journal Mol Pain Section Body Doc Link PMC2900238 Disease Relevance 0 Pain Relevance 0.41

General Comments

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